Antenatal depression and adversity in urban South Africa.
Antenatal depression and adversity in urban South Africa.
复制标题
南非城市的产前抑郁症和逆境。
DOI：
10.1016/j.jad.2016.05.052
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发表时间：
2016
影响因子：
6.6
通讯作者：
Honikman,Simone
中科院分区：
文献类型：
--
作者：
Heyningen,Thandivan;Myer,Landon;Onah,Michael;Tomlinson,Mark;Field,Sally;Honikman,Simone
背景在低收入和中等收入国家（LMIC），影响孕妇的常见精神障碍没有得到优先重视，尽管它们对孕产妇功能有致残作用，对儿童健康和发育有负面影响。我们调查的患病率产前抑郁症的危险因素，生活在逆境中的妇女在一个低资源，城市环境在开普敦，SouthAfrica.MethodsThe迷你神经精神访谈（迷你加）被用来衡量抑郁症的诊断患病率的妇女参加他们的第一次产前检查在初级水平，社区为基础的诊所。收集人口统计学数据，然后进行问卷调查，以衡量心理社会风险。分析研究抑郁症的诊断和心理社会风险变量之间的关联，和Logistic回归被用来调查预测因子为重性抑郁发作（MDE）。MINI定义的MDE患病率为22%，50%的抑郁症女性也表现出自杀倾向。MDE诊断与多种社会经济和心理社会风险因素显著相关，包括抑郁或焦虑史、食物不安全、威胁生命事件的经历和家庭支持感。回顾性收集的临床数据限制了我们的能力，以检查一些已知的危险因素为mental distress.ConclusionThese研究结果证实了高患病率的MDE孕妇在LMIC设置。在妇女面临多种风险的环境中，抑郁症的发病率可能会增加。这些风险因素应考虑到孕产妇心理健康干预计划。
BackgroundIn low and middle-income countries (LMIC), common mental disorders affecting pregnant women receive low priority, despite their disabling effect on maternal functioning and negative impact on child health and development. We investigated the prevalence of risk factors for antenatal depression among women living in adversity in a low-resource, urban setting in Cape Town, South Africa.MethodsThe MINI Neuropsychiatric Interview (MINI Plus) was used to measure the diagnostic prevalence of depression amongst women attending their first antenatal visit at a primary-level, community-based clinic. Demographic data were collected followed by administration of questionnaires to measure psychosocial risk. Analysis examined the association between diagnosis of depression and psychosocial risk variables, and logistic regression was used to investigate predictors for major depressive episode (MDE).ResultsAmong 376 women participating, the mean age was 26 years. The MINI-defined prevalence of MDE was 22%, with 50% of depressed women also expressing suicidality. MDE diagnosis was significantly associated with multiple socioeconomic and psychosocial risk factors, including a history of depression or anxiety, food insecurity, experience of threatening life events and perceived support from family.LimitationsThe use of self-report measures may have led to recall bias. Retrospective collection of clinical data limited our ability to examine some known risk factors for mental distress.ConclusionThese findings confirm the high prevalence of MDE among pregnant women in LMIC settings. Rates of depression may be increased in settings where women are exposed to multiple risks. These risk factors should be considered when planning maternal mental health interventions.
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作者：
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DOI：
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