Physics of cellular energy metabolism
Physics of cellular energy metabolism
复制标题
细胞能量代谢物理学
DOI:
10.1080/00107514.2022.2073046
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发表时间:
2022
影响因子:
2
通讯作者:
Barnes S
中科院分区:
文献类型:
--
作者:
Barnes S
Contributions to the field of cellular energy metabolism have been dominated by biochemistry. Over the past decade, however, several physics-based approaches have been introduced. Oscillations are an intrinsic aspect of all living systems, from fluctuating substrate levels within cells to changes in electrical potential across membranes. Utilising physics-based approaches to analyse these time-dependent signals reveals pockets of predictable stability. By embracing the nonlinear, time-varying and open nature of cellular dynamics, new network-based approaches to modelling cells are emerging, capable of effectively replicating measured time-series data. These new approaches promise to bring greater comprehension of how various illnesses affect the cells, and indeed, to novel treatments or diagnostic methods.
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