Population genomics of rapid adaptation by soft selective sweeps.

Population genomics of rapid adaptation by soft selective sweeps.
复制标题

DOI:
10.1016/j.tree.2013.08.003
复制
发表时间:
2013-11
影响因子:
16.8
通讯作者:
Petrov DA
Petrov DA
中科院分区:
生物学1区
文献类型:
--
作者:
Messer PW;Petrov DA

文献摘要

参考文献

被引文献

相似文献

生物体通常可以惊人地快速适应进化挑战,例如杀虫剂或抗生素的应用,这表明适应性遗传变异的供应丰富。在这些情况下,适应通常会产生“软”选择性扫描,即多个适应性等位基因同时扫描整个种群,这要么是因为等位基因已经作为常设遗传变异存在,要么是因为反复出现的从头突变而独立出现。大多数众所周知的快速分子适应的例子确实显示了这种软选择性扫描的特征。在这里,我们回顾了我们目前的理解的机制,产生软扫描和用于识别人口基因组数据的方法。我们认为,软扫描可能是许多物种的主要适应模式。
Organisms can often adapt surprisingly quickly to evolutionary challenges, such as the application of pesticides or antibiotics, suggesting an abundant supply of adaptive genetic variation. In these situations, adaptation should commonly produce “soft” selective sweeps, where multiple adaptive alleles sweep through the population at the same time, either because the alleles were already present as standing genetic variation or arose independently by recurrent de novo mutations. Most well-known examples of rapid molecular adaptation indeed show signatures of such soft selective sweeps. Here we review our current understanding of the mechanisms that produce soft sweeps and the approaches used for their identification in population genomic data. We argue that soft sweeps might be the dominant mode of adaptation in many species.
DOI: 10.1086/421051
发表时间: 2004-06-01
影响因子: 9.8
作者:
Bersaglieri, T;Sabeti, PC;Hirschhorn, JN
通讯作者: Hirschhorn, JN
DOI: 10.1371/journal.pone.0012303
发表时间: 2010-08-20
期刊: PloS one
影响因子: 3.7
作者:
Fischer W;Ganusov VV;Giorgi EE;Hraber PT;Keele BF;Leitner T;Han CS;Gleasner CD;Green L;Lo CC;Nag A;Wallstrom TC;Wang S;McMichael AJ;Haynes BF;Hahn BH;Perelson AS;Borrow P;Shaw GM;Bhattacharya T;Korber BT
通讯作者: Korber BT
DOI: 10.1111/j.1558-5646.2012.01669.x
发表时间: 2012-10-01
期刊: EVOLUTION
影响因子: 3.3
作者:
Domingues, Vera S.;Poh, Yu-Ping;Hoekstra, Hopi E.
通讯作者: Hoekstra, Hopi E.
DOI: 10.1016/j.ajhg.2007.09.012
发表时间: 2008-01-01
影响因子: 9.8
作者:
Enattah, Nabil Sabri;Jensen, Tine G. K.;Peltonen, Leena
通讯作者: Peltonen, Leena
DOI: 10.1016/j.tpb.2004.04.002
发表时间: 2004-09-01
影响因子: 1.4
作者:
Durrett, R;Schweinsberg, J
通讯作者: Schweinsberg, J