Drug Use Disorders and Violence: Associations With Individual Drug Categories.
Drug Use Disorders and Violence: Associations With Individual Drug Categories.
复制标题
DOI：
10.1093/epirev/mxaa006
复制
发表时间：
2020-01-31
影响因子：
5.5
通讯作者：
Fazel S
中科院分区：
文献类型：
--
作者：
Zhong S;Yu R;Fazel S
我们进行了一项系统的回顾，研究了个别药物类别和暴力结果之间的联系。我们检索了主要病例对照和队列研究，这些研究报告了使用经验证的临床标准诊断为药物使用障碍的个体中对他人的暴力风险，遵循系统评价和荟萃分析指南的首选报告项目。我们确定了1990年至2019年期间发表的18项研究，报告了来自591，411名药物使用障碍患者的数据。我们报告了不同类别的药物使用障碍与非药物使用障碍的暴力风险的比值比。我们发现大多数药物类别的比值比范围为0.8至25.0，多药使用障碍患者的比值比通常较高。此外，我们通过亚组和荟萃回归分析探讨了研究间异质性的来源。队列研究报告的暴力风险低于病例对照报告（比值比= 2.7（95%置信区间（CI）：2.1，3.5）与6.6（95%CI：5.1，8.6）），并且当结果是任何暴力而不是亲密伴侣暴力时，相关性更强（比值比= 5.7（95% CI：3.8，8.6）vs. 1.7（95% CI：1.4，2.1）），这与荟萃回归的结果一致。总的来说，这些研究结果突出了预防和治疗药物使用障碍对减少暴力风险和相关发病率的潜在影响。
We conducted a systematic review that examined the link between individual drug categories and violent outcomes. We searched for primary case-control and cohort investigations that reported risk of violence against others among individuals diagnosed with drug use disorders using validated clinical criteria, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. We identified 18 studies published during 1990–2019, reporting data from 591,411 individuals with drug use disorders. We reported odds ratios of the violence risk in different categories of drug use disorders compared with those without. We found odds ratios ranging from 0.8 to 25.0 for most individual drug categories, with generally higher odds ratios among individuals with polydrug use disorders. In addition, we explored sources of between-study heterogeneity by subgroup and meta-regression analyses. Cohort investigations reported a lower risk of violence than case-control reports (odds ratio = 2.7 (95% confidence interval (CI): 2.1, 3.5) vs. 6.6 (95% CI: 5.1, 8.6)), and associations were stronger when the outcome was any violence rather than intimate partner violence (odds ratio = 5.7 (95% CI: 3.8, 8.6) vs. 1.7 (95% CI: 1.4, 2.1)), which was consistent with results from the meta-regression. Overall, these findings highlight the potential impact of preventing and treating drug use disorders on reducing violence risk and associated morbidities.
登录
查看更多内容
影响因子：
1.4
作者：
Christoffersen, MN;Francis, B;Soothill, K
通讯作者：
Soothill, K
影响因子：
120.7
作者：
Chang, Zheng;Lichtenstein, Paul;Fazel, Seena
通讯作者：
Fazel, Seena
影响因子：
73.3
作者：
Degenhardt, Louisa;Glantz, Meyer;Kessler, Ronald C.
通讯作者：
Kessler, Ronald C.
影响因子：
2
作者：
Asberg, Kia;Renk, Kimberly
通讯作者：
Renk, Kimberly
影响因子：
2.8
作者：
Duke, Aaron A.;Smith, Kathryn M. Z.;McKee, Sherry A.
通讯作者：
McKee, Sherry A.