Methods of induction of labour: a systematic review.

Methods of induction of labour: a systematic review.
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DOI:
10.1186/1471-2393-11-84
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发表时间:
2011-10-27
影响因子:
3.1
通讯作者:
Keeton KL
Keeton KL
中科院分区:
医学3区
文献类型:
--
作者:
Mozurkewich EL;Chilimigras JL;Berman DR;Perni UC;Romero VC;King VJ;Keeton KL

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引产率正在提高。我们进行了这项系统性综述,以评估支持使用每种引产方法的证据。我们列出了引产方法,然后回顾了支持每种方法的证据。我们使用多个术语和组合检索了1980年至2010年11月期间的MEDLINE和科克伦图书馆,包括分娩、引产/或引产、前列腺素或前列腺素、米索前列醇、Cytotec、16,16-二甲基前列腺素E2或E2、地诺前列酮; Prepidil、Cervidil、地诺前列素、卡前列素或hemabate;前列腺素、催产素、米索前列醇、膜清扫或膜剥离、尿道切开术、球囊导管或Foley导管、吸湿扩张器、昆布、曲马多、盐水注射、乳头刺激、性交、针灸、蓖麻油、草药。我们对支持每种方法的文献进行了最佳证据审查。我们确定了2048篇摘要,并审查了283篇全文文章。我们优先纳入高质量的系统评价或大型随机试验。如果没有这样的研究存在,我们纳入了从较小的随机或半随机试验中获得的最佳证据。全文共收录46篇文章。我们对每篇纳入的文章进行了质量评级,对每篇文献进行了证据强度评级。前列腺素E2(PGE 2)和阴道米索前列醇在24小时内阴道分娩比催产素更有效,但与更多的子宫过度刺激有关。与PGE 2和米索前列醇相比,机械方法减少了子宫过度刺激,但与其他方法相比,增加了孕产妇和新生儿的感染发病率。膜清扫减少过期妊娠。大多数纳入的研究规模太小,无法评估罕见不良结局的风险。需要研究来确定许多诱导方法的益处和危害。
Rates of labour induction are increasing. We conducted this systematic review to assess the evidence supporting use of each method of labour induction. We listed methods of labour induction then reviewed the evidence supporting each. We searched MEDLINE and the Cochrane Library between 1980 and November 2010 using multiple terms and combinations, including labor, induced/or induction of labor, prostaglandin or prostaglandins, misoprostol, Cytotec, 16,16,-dimethylprostaglandin E2 or E2, dinoprostone; Prepidil, Cervidil, Dinoprost, Carboprost or hemabate; prostin, oxytocin, misoprostol, membrane sweeping or membrane stripping, amniotomy, balloon catheter or Foley catheter, hygroscopic dilators, laminaria, dilapan, saline injection, nipple stimulation, intercourse, acupuncture, castor oil, herbs. We performed a best evidence review of the literature supporting each method. We identified 2048 abstracts and reviewed 283 full text articles. We preferentially included high quality systematic reviews or large randomised trials. Where no such studies existed, we included the best evidence available from smaller randomised or quasi-randomised trials. We included 46 full text articles. We assigned a quality rating to each included article and a strength of evidence rating to each body of literature. Prostaglandin E2 (PGE2) and vaginal misoprostol were more effective than oxytocin in bringing about vaginal delivery within 24 hours but were associated with more uterine hyperstimulation. Mechanical methods reduced uterine hyperstimulation compared with PGE2 and misoprostol, but increased maternal and neonatal infectious morbidity compared with other methods. Membrane sweeping reduced post-term gestations. Most included studies were too small to evaluate risk for rare adverse outcomes. Research is needed to determine benefits and harms of many induction methods.
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