A brief history of human autosomes.
A brief history of human autosomes.
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人类常染色体简史。
DOI：
10.1098/rstb.1999.0490
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
David Haig
中科院分区：
文献类型：
--
作者：
David Haig
比较基因定位和染色体彩绘允许尝试重建祖先的核型。现代人类的染色体组型被认为与卡他鼻灵长类最近的共同祖先的染色体组型有两个主要的重排。第一个是祖先染色体的分裂，产生了人类14号和15号染色体的同源物。这种分裂发生在长臂猿与人类和其他猿类分化之前。第二个是两个祖先染色体融合形成人类2号染色体。这种融合发生在人类和黑猩猩分化之后。再往前追溯，人类3号和21号染色体的同源物是由一个祖先连锁群的分裂形成的，该连锁群结合了两个人类染色体的基因座，而人类12号和22号染色体的同源物是由两个祖先染色体之间的相互易位形成的。这两个事件都发生在我们最近的共同祖先狐猴之后的某个时候。不太直接的证据表明，人类8号、16号和19号染色体的长臂和短臂在这位祖先身上是分开的。最后，灵长类和偶蹄类最近的共同祖先被认为拥有一条结合了人类4号和8p号染色体的染色体，一条结合了人类16号和19号染色体的染色体，以及一条结合了人类2p号和20号染色体的染色体。
Comparative gene mapping and chromosome painting permit the tentative reconstruction of ancestral karyotypes. The modern human karyotype is proposed to differ from that of the most recent common ancestor of catarrhine primates by two major rearrangements. The first was the fission of an ancestral chromosome to produce the homologues of human chromosomes 14 and 15. This fission occurred before the divergence of gibbons from humans and other apes. The second was the fusion of two ancestral chromosomes to form human chromosome 2. This fusion occurred after the divergence of humans and chimpanzees. Moving further back in time, homologues of human chromosomes 3 and 21 were formed by the fission of an ancestral linkage group that combined loci of both human chromosomes, whereas homologues of human chromosomes 12 and 22 were formed by a reciprocal translocation between two ancestral chromosomes. Both events occurred at some time after our most recent common ancestor with lemurs. Less direct evidence suggests that the short and long arms of human chromosomes 8, 16 and 19 were unlinked in this ancestor. Finally, the most recent common ancestor of primates and artiodactyls is proposed to have possessed a chromosome that combined loci from human chromosomes 4 and 8p, a chromosome that combined loci from human chromosomes 16q and 19q, and a chromosome that combined loci from human chromosomes 2p and 20.
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比较地图：哺乳动物拼图游戏。
影响因子：
4
作者：
Eppig,JT;Nadeau,JH
通讯作者：
Nadeau,JH
DOI：
10.1093/oxfordjournals.jhered.a111106
发表时间：
1991-09
期刊：
The Journal of heredity
影响因子：
--
作者：
H. Wichman;C. Payne;Oliver A. Ryder;Meredith J. Hamilton;M. Maltbie;Robert J. Baker
通讯作者：
H. Wichman;C. Payne;Oliver A. Ryder;Meredith J. Hamilton;M. Maltbie;Robert J. Baker
人类 19 号染色体上纤连蛋白受体 β 亚基样序列的遗传和物理作图以及群体研究。
影响因子：
4.4
作者：
Giuffra,LA;Lichter,P;Wu,JS;Kennedy,JL;Pakstis,AJ;Rogers,J;Kidd,JR;Harley,H;Jenkins,T;Ward,DC
通讯作者：
Ward,DC
人类 17 号染色体基因座与狗 9 号和 5 号染色体的物理和连锁图谱。
DOI：
10.1006/geno.1997.4723
发表时间：
1997
期刊：
Genomics.
影响因子：
--
作者：
Werner,P;Raducha,MG;Prociuk,U;Henthorn,PS;Patterson,DF
通讯作者：
Patterson,DF
影响因子：
9.8
作者：
T. Hassold;Michelle C. Merrill;K. Adkins;'. S. Freeman;S. Sherman
通讯作者：
T. Hassold;Michelle C. Merrill;K. Adkins;'. S. Freeman;S. Sherman