The role of the corpus callosum in language network connectivity in children.
The role of the corpus callosum in language network connectivity in children.
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DOI：
10.1111/desc.13031
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发表时间：
2021-03
影响因子：
3.7
通讯作者：
Seidl R
中科院分区：
文献类型：
--
作者：
Bartha-Doering L;Kollndorfer K;Schwartz E;Fischmeister FPS;Alexopoulos J;Langs G;Prayer D;Kasprian G;Seidl R
The specific role of the corpus callosum (CC) in language network organization remains unclear, two contrasting models have been proposed: inhibition of homotopic areas allowing for independent functioning of the hemispheres versus integration of information from both hemispheres. This study aimed to add to this discussion with the first investigation of language network connectivity in combination with CC volume measures. In 38 healthy children aged 6–12, we performed task‐based functional magnetic resonance imaging to measure language network connectivity, used structural magnetic resonance imaging to quantify CC subsection volumes, and administered various language tests to examine language abilities. We found an increase in left intrahemispheric and bilateral language network connectivity and a decrease in right intrahemispheric connectivity associated with larger volumes of the posterior, mid‐posterior, and central subsections of the CC. Consistent with that, larger volumes of the posterior parts of the CC were significantly associated with better verbal fluency and vocabulary, the anterior CC volume was positively correlated with verbal span. Thus, children with larger volumes of CC subsections showed increased interhemispheric language network connectivity and were better in different language domains. This study presents the first evidence that the CC is directly linked to language network connectivity and underlines the excitatory role of the CC in the integration of information from both hemispheres. In 38 healthy children aged 6–12, the present study measured language network connectivity, corpus callosum subsection volumes, and language abilities. Children with larger volumes of CC subsections showed increased interhemispheric language network connectivity and were better in different language domains. The present study suggests that the corpus callosum is directly linked to language network connectivity and underlines the excitatory role of the corpus callosum in the integration of information from both hemispheres. .
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影响因子：
5.3
作者：
Chovsepian A;Empl L;Correa D;Bareyre FM
通讯作者：
Bareyre FM
当两个比一个更好时：双边介质颞叶的贡献与儿童和青少年更好的词汇技能相关。
影响因子：
2.5
作者：
Bartha-Doering L;Novak A;Kollndorfer K;Kasprian G;Schuler AL;Berl MM;Fischmeister FPS;Gaillard WD;Alexopoulos J;Prayer D;Seidl R
通讯作者：
Seidl R
影响因子：
2.5
作者：
COOK, ND
通讯作者：
COOK, ND
影响因子：
1.9
作者：
Caldu, Xavier;Narberhaus, Ana;Botet, Francesc
通讯作者：
Botet, Francesc
影响因子：
3.6
作者：
Chu, Ronald;Meltzer, Jed A.;Bitan, Tali
通讯作者：
Bitan, Tali