Translation drives mRNA quality control.
Translation drives mRNA quality control.
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DOI:
10.1038/nsmb.2301
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发表时间:
2012-06-05
影响因子:
16.8
通讯作者:
Green, Rachel
中科院分区:
文献类型:
--
作者:
Shoemaker, Christopher J.;Green, Rachel
There are three predominant forms of co-translational mRNA surveillance: nonsense-mediated decay (NMD), no-go decay (NGD) and non-stop decay (NSD). While discussion of these pathways often focuses on mRNA fate, there is growing consensus that there are other important outcomes of these processes that must be simultaneously considered. Here, we seek to highlight similarities between NMD, NGD and NSD and their likely origins on the ribosome during translation.
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