Force-sensitive afferents recruited during stance encode sensory depression in the contralateral swinging limb during locomotion.
Force-sensitive afferents recruited during stance encode sensory depression in the contralateral swinging limb during locomotion.
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DOI：
10.1111/nyas.12055
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发表时间：
2013-03
影响因子：
5.2
通讯作者：
Chang YH
中科院分区：
文献类型：
--
作者：
Hochman S;Hayes HB;Speigel I;Chang YH
Afferent feedback alters muscle activity during locomotion and must be tightly controlled. As primary afferent depolarization-induced presynaptic inhibition (PAD-PSI) regulates afferent signaling, we investigated hind limb PAD-PSI during locomotion in an in vitro rat spinal cord-hind limb preparation. We compared the relation of PAD-PSI, measured as dorsal root potentials (DRPs), to observed ipsilateral and contralateral limb endpoint forces. Afferents activated during stance-phase force strongly and proportionately influenced DRP magnitude in the swinging limb. Responses increased with locomotor frequency. Electrical stimulation of contralateral afferents also preferentially evoked DRPs in the opposite limb during swing (flexion). Nerve lesioning in conjunction with kinematic results support a prominent contribution from toe Golgi tendon organ afferents. Thus, force-dependent afferent feedback during stance binds interlimb sensorimotor state to a proportional PAD-PSI in the swinging limb, presumably to optimize interlimb coordination. These results complement known actions of ipsilateral afferents on PAD-PSI during locomotion.
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DOI：
10.1111/j.1748-1716.1983.tb07267.x
发表时间：
1983-01-01
期刊：
ACTA PHYSIOLOGICA SCANDINAVICA
影响因子：
--
作者：
ANDERSSON, O;GRILLNER, S
通讯作者：
GRILLNER, S
影响因子：
5.5
作者：
Bannatyne, B. A.;Liu, T. T.;Maxwell, D. J.
通讯作者：
Maxwell, D. J.
影响因子：
2.9
作者：
Beloozerova, IN;Rossignol, S
通讯作者：
Rossignol, S
影响因子：
2.9
作者：
DUYSENS, J;PEARSON, KG
通讯作者：
PEARSON, KG
影响因子：
5.5
作者：
FERRELL, WR
通讯作者：
FERRELL, WR