Lymphatic Vessels: A Potential Approach to the Treatment of Atherosclerosis?
Lymphatic Vessels: A Potential Approach to the Treatment of Atherosclerosis?
复制标题
淋巴管：治疗动脉粥样硬化的潜在方法？
DOI：
10.1089/lrb.2018.0015
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发表时间：
2018-12
影响因子：
1.4
通讯作者：
Guanghui Yi
中科院分区：
文献类型：
--
作者：
Zhi Zheng;Kun Ren;Xiaoshan Peng;Xiao Zhu;Guanghui Yi
Many basic and clinical studies have demonstrated that atherosclerosis is a chronic inflammatory disease. Although there are many factors affecting atherosclerosis, the role of lymphatic vessels in this disease has been neglected. Traditionally, lymphatic vessels have been considered to be passages for transporting interstitial fluid to the blood circulation. However, as early as the last century, researchers found that there are numerous lymphatic vessels surrounding sites of atherosclerosis; however, the relationship between lymphatic vessels and atherosclerosis is not clear. With further research, lymphatic vessels were determined to be involved in the induction and resolution of arterial inflammation and also to play a positive role in plaque cholesterol transport. There are abundant immune cells around atherosclerosis, and these immune cells not only have a significant impact on plaque formation but also affect local lymphangiogenesis (IAL). This promotion of IAL seems to relieve the progression of atherosclerosis. Therefore, research into the relationship between lymphatic vessels and atherosclerosis is of great importance for improving atherosclerosis treatment. This review highlights what is known about the relationship between lymphatic vessels and atherosclerosis, including the effect of immune cells on IAL, and reverse cholesterol transport. In addition, we present some of our views on the improvement of atherosclerosis treatment, which have significant clinical value in research.
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影响因子：
5.4
作者：
A. Zumsteg;G. Christofori
通讯作者：
A. Zumsteg;G. Christofori
影响因子：
16.8
作者：
Koltsova EK;Ley K
通讯作者：
Ley K
炎症引起的白细胞跨淋巴管内皮迁移的机制。
影响因子：
15.3
作者：
Johnson, Louise A;Clasper, Steven;Holt, Andrew P;Lalor, Patricia F;Baban, Dilair;Jackson, David G
通讯作者：
Jackson, David G
DOI：
10.1007/978-3-7091-1646-3_13
发表时间：
2014
期刊：
Advances in anatomy, embryology, and cell biology
影响因子：
--
作者：
Cathrin Pollmann;R. Hägerling;F. Kiefer
通讯作者：
Cathrin Pollmann;R. Hägerling;F. Kiefer
影响因子：
32.4
作者：
Kataru, Raghu P.;Kim, Honsoul;Koh, Gou Young
通讯作者：
Koh, Gou Young