A comparison of three types of web-based inhibition training for the reduction of alcohol consumption in problem drinkers: study protocol.

A comparison of three types of web-based inhibition training for the reduction of alcohol consumption in problem drinkers: study protocol.
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DOI:
10.1186/1471-2458-14-796
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发表时间:
2014-08-05
期刊:
影响因子:
4.5
通讯作者:
Field M
Field M
中科院分区:
医学2区
文献类型:
--
作者:
Jones A;McGrath E;Houben K;Nederkoorn C;Robinson E;Field M

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有问题的饮酒者的抑制控制能力较差(去抑制)。此前的研究表明,各种形式的“抑制训练”可以在实验室和短期随访中减少饮酒量,但其长期功效和作用机制尚不清楚。在这项二期随机对照试验中,我们将比较三种形式的抑制训练和控制干预(通过互联网在四个星期内分多次进行)对重度饮酒者饮酒量的影响。有兴趣减少饮酒量的酗酒者将接受简短的干预,并在一周内监测自己的酒精摄入量,然后被随机分配到四个治疗组之一: 1. 一般抑制训练; 2.特定线索抑制训练; 3. 禁酒训练;或 4. 控制。他们将在四个星期内通过互联网完成最多 14 期培训,并在培训期结束后继续进行六周的跟踪。主要结果指标是减少饮酒量和酗酒天数。禁欲天数是次要结果指标。我们还将调查训练后抑制控制和自动酒精情感关联的变化。这项研究将确定基于网络的抑制训练是否可以帮助有饮酒问题的人减少酒精摄入量,并将确定哪种形式的抑制训练最有效。试用注册号:ISRCTN55671858。
Problem drinkers have poor inhibitory control (disinhibition). Previous studies have demonstrated that various forms of ‘inhibition training’ can reduce alcohol consumption in the laboratory and at short-term follow-up, but their longer-term efficacy and mechanisms of action are unknown. In this phase 2 randomised controlled trial we will contrast the effects of three forms of inhibition training and a control intervention, delivered via the Internet in multiple sessions over four weeks, on alcohol consumption in heavy drinkers. Heavy drinkers who are interested in reducing their alcohol consumption will receive a brief intervention and will monitor their own alcohol intake for one week before being randomised to one of four treatment groups: 1. General inhibition training; 2. Cue-Specific inhibition training; 3. Alcohol No-Go training; or 4. Control. They will complete up to 14 sessions of training via the Internet over a four-week period, and will be followed-up for a further six weeks after the end of the training period. Primary outcome measures are reductions in alcohol consumption and heavy drinking days. The number of abstinent days is a secondary outcome measure. We will also investigate changes in inhibitory control and automatic alcohol affective associations in response to training. This study will establish if web-based inhibition training can help problem drinkers to reduce their alcohol intake, and it will identify which form(s) of inhibition training are most effective. Trial Registation number: ISRCTN55671858.
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