Review of current and future therapeutics in ABPA.
Review of current and future therapeutics in ABPA.
复制标题
回顾ABPA的当前和未来治疗剂。
DOI：
10.1177/20406223211047003
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发表时间：
2021
影响因子：
3.5
通讯作者：
Shah A
中科院分区：
文献类型：
--
作者：
Lewington-Gower E;Chan L;Shah A
Allergic bronchopulmonary aspergillosis is an allergic pulmonary condition caused by hypersensitivity to antigens of Aspergillus sp. found most commonly in patients with underlying asthma or cystic fibrosis. Host factors which alter the innate and adaptive immune responses to this abundant airborne fungus contribute to the development of chronic airway inflammation, bronchiectasis, and fibrosis. Traditionally, treatment has focussed on reducing fungal burden and immune response to fungal antigens. However, a significant proportion of patients continue to suffer recurrent exacerbations with progressive lung damage, and the side effect burden of existing treatments is high. New treatments including novel antifungal agents, monoclonal antibodies against aspects of the adaptive immune response as well as targeted immunotherapies may be better tolerated and achieve improved outcomes but have not yet been studied in large-scale randomised control trials.
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DOI：
10.1016/j.jaci.2021.03.015
发表时间：
2021-05
期刊：
The Journal of allergy and clinical immunology
影响因子：
--
作者：
Bartemes KR;Kita H
通讯作者：
Kita H
影响因子：
14.2
作者：
Burks, A. Wesley;Calderon, Moises A.;Akdis, Cezmi A.
通讯作者：
Akdis, Cezmi A.
影响因子：
6.1
作者：
Agarwal, R.;Chakrabarti, A.;Denning, D. W.
通讯作者：
Denning, D. W.
影响因子：
3.1
作者：
AMITANI, R;TAYLOR, G;WILSON, R
通讯作者：
WILSON, R
DOI：
10.4103/ijmr.ijmr_1187_19
发表时间：
2020-06
期刊：
The Indian journal of medical research
影响因子：
--
作者：
Agarwal R;Sehgal IS;Dhooria S;Muthu V;Prasad KT;Bal A;Aggarwal AN;Chakrabarti A
通讯作者：
Chakrabarti A