Sociability in a non-captive macaque population is associated with beneficial gut bacteria.
Sociability in a non-captive macaque population is associated with beneficial gut bacteria.
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DOI：
10.3389/fmicb.2022.1032495
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发表时间：
2022
影响因子：
5.2
通讯作者：
Burnet, Philip W. J.
中科院分区：
文献类型：
--
作者：
Johnson, Katerina V. -A.;Watson, Karli K.;Dunbar, Robin I. M.;Burnet, Philip W. J.
关键词：
社会行为和微生物组之间的关系是相互的。对野生动物种群，特别是灵长类社会群体的研究揭示了社会互动在微生物传播中的作用，而对实验室动物的研究表明，肠道微生物组可以影响行为的多个方面，包括社会行为。在这里，我们探讨了行为的变化，在非圈养动物种群的丰富度方面的特定细菌属。在恒河猴（Macaca mulatta）群体中评估基于梳理相互作用的社会行为，并与肠道微生物组数据相结合。我们的分析重点是以前与啮齿动物和人类的社交和自闭症行为有关的微生物组属。我们表明，在这个猕猴种群，这些属中的一些也涉及到一个人的倾向，从事社会交往。有趣的是，我们发现几个与社会性正相关的属，如粪杆菌属，因其对健康的有益作用和抗炎特性而闻名。相比之下，链球菌属，其中包括致病物种，是更丰富的社会交往较少的猕猴。我们的研究结果表明，微生物的丰度随个体的社会行为而变化，也有功能联系到宿主的免疫状态。总的来说，这些发现突出了动物群体中社会行为、微生物组组成和健康之间的联系。
The relationship between social behaviour and the microbiome is known to be reciprocal. Research in wild animal populations, particularly in primate social groups, has revealed the role that social interactions play in microbial transmission, whilst studies in laboratory animals have demonstrated that the gut microbiome can affect multiple aspects of behaviour, including social behaviour. Here we explore behavioural variation in a non-captive animal population with respect to the abundance of specific bacterial genera. Social behaviour based on grooming interactions is assessed in a population of rhesus macaques (Macaca mulatta), and combined with gut microbiome data. We focus our analyses on microbiome genera previously linked to sociability and autistic behaviours in rodents and humans. We show in this macaque population that some of these genera are also related to an individual’s propensity to engage in social interactions. Interestingly, we find that several of the genera positively related to sociability, such as Faecalibacterium, are well known for their beneficial effects on health and their anti-inflammatory properties. In contrast, the genus Streptococcus, which includes pathogenic species, is more abundant in less sociable macaques. Our results indicate that microorganisms whose abundance varies with individual social behaviour also have functional links to host immune status. Overall, these findings highlight the connections between social behaviour, microbiome composition, and health in an animal population.
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影响因子：
17.1
作者：
Ardeshir A;Narayan NR;Méndez-Lagares G;Lu D;Rauch M;Huang Y;Van Rompay KK;Lynch SV;Hartigan-O'Connor DJ
通讯作者：
Hartigan-O'Connor DJ
DOI：
10.1038/ismej.2012.8
发表时间：
2012-08
期刊：
The ISME journal
影响因子：
--
作者：
通讯作者：
--
影响因子：
4.6
作者：
Brent LJ;Heilbronner SR;Horvath JE;Gonzalez-Martinez J;Ruiz-Lambides A;Robinson AG;Skene JH;Platt ML
通讯作者：
Platt ML
影响因子：
3.6
作者：
Amato, Katherine R.;Van Belle, Sarie;Leigh, Steven R.
通讯作者：
Leigh, Steven R.
影响因子：
9.2
作者：
Almeling, Laura;Hammerschmidt, Kurt;Fischer, Julia
通讯作者：
Fischer, Julia