Assessment of regional myocardial perfusion with thallium imaging during transient left anterior descending coronary arterial occlusion during angioplasty.
Assessment of regional myocardial perfusion with thallium imaging during transient left anterior descending coronary arterial occlusion during angioplasty.
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血管成形术期间短暂左前降支冠状动脉闭塞期间用铊成像评估局部心肌灌注。
DOI：
10.1016/0002-9149(86)90678-8
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Boucher,CA
中科院分区：
文献类型：
--
作者：
Wiske,PS;Palacios,I;Block,PC;O'Gara,P;Strauss,HW;Okada,RD;Boucher,CA
为了确定通过单个冠状动脉狭窄灌注的危险区域，在10例单支冠状动脉左前降支疾病患者的一系列经皮冠状动脉腔内成形术（PTCA）球囊扩张术的最后一次开始时，将铊-201，2 mCi注入肺动脉。在PTCA后立即开始成像。动脉铊活性在注射后30秒达到峰值，并在球囊放气时降至峰值活性的34 ± 6%（平均值±平均值的标准误差）。对运动与PTCA期间的局部铊活性进行定性和定量评分。使用计算机定量程序，允许自动重新排列和标准化的2个初始铊图像。与PTCA扫描相比，运动扫描仅平均定量后部活动较低（93 ± 1% vs 86 ± 2%，p < 0.05）。其他5个节段的平均评分无差异。有初始铊分布没有定性差异，也没有定性或定量的差异，异常段的数量或活动的严重程度降低，在活动最低的段。总之，局部铊心肌分布与一个单一的严重狭窄与注射在峰值运动是类似的完全闭塞后。
To define the jeopardized territory perfused through a single coronary arterial stenosis, thallium-201, 2 mCi, was injected into the pulmonary artery at the onset of the last of a series of percutaneous transluminal coronary angioplasty (PTCA) balloon inflations in 10 patients with single-vessel left anterior descending coronary artery disease. Imaging was begun immediately after PTCA. Arterial thallium activity peaked 30 seconds after injection and decreased to 34 ± 6% (mean ± standard error of the mean) of peak activity at the time of balloon deflation. Regional thallium activity during exercise vs PTCA was scored qualitatively and quantitatively. A computer quantification program was used that permitted automatic realignment and normalization of the 2 initial thallium images. Only mean quantitative posterior activity was lower (93 ± 1% vs 86 ± 2%, p < 0.05) on exercise scans compared with PTCA scans. The other 5 segments showed no difference in mean scores. There were no qualitative differences in initial thallium distribution, nor were there qualitative or quantitative differences in the number of abnormal segments or severity of reduction in activity in the segment with the lowest activity. In conclusion, regional thallium myocardial distribution with a single severe stenoses with injection during peak exercise is similar to that after complete coronary occlusion.
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影响因子：
11.2
作者：
A. Raick;K. Thumm;B. R. Chivers
通讯作者：
B. R. Chivers
影响因子：
10.4
作者：
T. Slaga
通讯作者：
T. Slaga
影响因子：
64.8
作者：
HENNINGS, H;SHORES, R;YUSPA, SH
通讯作者：
YUSPA, SH
基于小鼠皮肤引发促进模型数据的遗传毒性致癌物风险评估方法。
影响因子：
10.4
作者：
F. Burns;R. Albert;B. Altshuler;E. Morris
通讯作者：
E. Morris
DOI：
--
发表时间：
1941
期刊：
影响因子：
--
作者：
I. Berenblum
通讯作者：
I. Berenblum