Joint Representation of Spatial and Phonetic Features in the Human Core Auditory Cortex.

Joint Representation of Spatial and Phonetic Features in the Human Core Auditory Cortex.
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人类核心听觉皮层空间和语音特征的联合表示。

DOI:
10.1016/j.celrep.2018.07.076
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发表时间:
2018
期刊:
影响因子:
8.8
通讯作者:
Mesgarani,Nima
Mesgarani,Nima
中科院分区:
生物学1区
文献类型:
--
作者:
Patel,Prachi;Long,LauraK;Herrero,JoseL;Mehta,AsheshD;Mesgarani,Nima

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人类听觉皮层同时处理语音并确定说话者在空间中的位置。人类的神经影像学研究已经暗示了核心听觉区域在处理声音的频谱时间和空间内容;然而,这些特征是如何一起表示的还不清楚。我们直接记录了人类受试者在核心听觉区双侧植入深度电极,因为他们听了来自不同方向的语音。我们发现了空间和spectrotemporal语音特征的局部和联合选择性,其中空间和spectrotemporal特征彼此独立地组织。这种表示能够成功地解码空间和语音信息。此外,我们发现,扬声器的位置不改变电极的spectrotemporal调谐,而是调制它们的平均响应水平。我们的研究结果有助于定义在人类听觉皮层的反应的功能组织,更准确的语音处理的神经生理模型的影响。
The human auditory cortex simultaneously processes speech and determines the location of a speaker in space. Neuroimaging studies in humans have implicated core auditory areas in processing the spectrotemporal and the spatial content of sound; however, how these features are represented together is unclear. We recorded directly from human subjects implanted bilaterally with depth electrodes in core auditory areas as they listened to speech from different directions. We found local and joint selectivity to spatial and spectrotemporal speech features, where the spatial and spectrotemporal features are organized independently of each other. This representation enables successful decoding of both spatial and phonetic information. Furthermore, we found that the location of the speaker does not change the spectrotemporal tuning of the electrodes but, rather, modulates their mean response level. Our findings contribute to defining the functional organization of responses in the human auditory cortex, with implications for more accurate neurophysiological models of speech processing.
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