Mapping of heavy chain genes for mouse immunoglobulins M and D.
Mapping of heavy chain genes for mouse immunoglobulins M and D.
复制标题
小鼠免疫球蛋白 M 和 D 的重链基因图谱。
作者：
C. Liu;P. Tucker;J. Mushinski;F. Blattner
A single DNA fragment containing both mu and delta immunoglobulin heavy chain genes has been cloned from normal BALB/c mouse liver DNA with a new lambda phage vector Charon 28. The physical distance between the membrane terminal exon of mu and the first domain of delta is 2466 base pairs, with delta on the 3' side of mu. A single transcript could contain a variable region and both mu and delta constant regions. The dual expression of immunoglobulins M and D on spleen B cells may be due to alternate splicing of this transcript.
小鼠 IgD 结构异质性的遗传控制。
DOI：
10.1073/pnas.77.7.4256
发表时间：
1980
影响因子：
11.1
作者：
Pollock,RR;Dorf,ME;Mescher,MF
通讯作者：
Mescher,MF