Caffeine improves contrast sensitivity of freely moving rats
Caffeine improves contrast sensitivity of freely moving rats
复制标题
咖啡因提高自由活动大鼠的对比敏感度
DOI:
10.1016/j.physbeh.2018.11.014
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发表时间:
2019
期刊:
影响因子:
--
通讯作者:
Shimegi S
中科院分区:
文献类型:
--
作者:
Tsunoda K;Sato A;Kurata R;Mizuyama R;Shimegi S
Caffeine (1, 3, 7-trimethylxanthine) is a well-known central nervous system stimulant that affects various brain functions such as attention, memory and sensation. However, it remains unclear whether and how caffeine modulates visual ability such as contrast sensitivity (CS) and the CS-spatial frequency (SF) relationship. To investigate these points, we tested the effects of caffeine on the perceptual CS of rats under three SF conditions. CS was measured using a two-alternative forced choice (2AFC) grating detection task combined with a staircase method. Intraperitoneal administration of caffeine 30 min prior to the task improved CS in an SF-dependent manner, in which the improving effect was observed at 0.1 cycles/degree (cpd) of the optimal SF for rats but not at 0.5 or 1 cpd. We concluded that caffeine, a representative ingredient contained in foods or drinks consumed daily, leads to an improvement of perceptual visual sensitivity.
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影响因子:
5.3
作者:
Julie A. Williams;Jeff Comisarow;Jamie C. Day;H. Fibiger;Peter B. Reiner
通讯作者:
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影响因子:
1.6
作者:
D. Smith;J. Tong;G. Leigh
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G. Leigh
DOI:
10.1111/j.1755-3768.1939.tb04309.x
发表时间:
1939
期刊:
影响因子:
--
作者:
S. V. Kravkov
通讯作者:
S. V. Kravkov
影响因子:
1.3
作者:
Freeman, GL
通讯作者:
Freeman, GL
DOI:
--
发表时间:
1971
期刊:
影响因子:
--
作者:
E. Furchtgott
通讯作者:
E. Furchtgott