Night-to-night repeatability of supine-related obstructive sleep apnea.
Night-to-night repeatability of supine-related obstructive sleep apnea.
复制标题
仰卧相关的阻塞性睡眠呼吸暂停的每晚可重复性。
DOI：
10.1513/annalsats.201309-306oc
复制
发表时间：
2014
影响因子：
8.3
通讯作者：
G. Hamilton
中科院分区：
文献类型：
--
作者：
S. Joosten;F. O'Donoghue;P. Rochford;M. Barnes;Kais Hamza;T. Churchward;P. Berger;G. Hamilton
理由
阻塞性睡眠呼吸暂停（OSA）患者在仰卧位睡眠时发生呼吸事件的频率和严重程度更高。姿势矫正装置（PMD）可防止仰卧睡眠，尽管缺乏指导来帮助临床医生决定何时为患者使用PMD。为了使PMD有效治疗OSA，患者必须在仰卧位睡眠时持续经历呼吸事件，并且必须具有较低的非仰卧位呼吸暂停和呼吸不足指数（AHINS）。
目标
记录连续多导睡眠图上传统定义的仰卧位优势OSA的可重复性，确定是否可以通过改变仰卧位优势表型的定义来改善其一致性，并确定低AHINS是否可以在夜间重复。
方法
我们招募了75名患者，在两个不同的夜晚进行多导睡眠描记。根据传统和新的定义，患者每晚被分类为患有仰卧位OSA，并根据每晚的一致性对所使用的分类系统进行比较。
测量值和主要结果
夜间一致性水平最高的仰卧位OSA定义包括仰卧位AHI（AHIS）与AHINS比值≥4：1。此外，无论采用何种定义，男性患者之间存在一致性，但女性患者之间的一致性较差。AHINS <10个事件/小时从晚上到晚上是高度可重复的。
结论
AHIS：AHINS比率≥4：1且AHINS <10次事件/小时的男性代表夜间一致的仰卧位为主的OSA表型。该患者组可能受益于PMD治疗。
RATIONALE
Patients with obstructive sleep apnea (OSA) experience respiratory events with greater frequency and severity while in the supine sleeping position. Postural modification devices (PMDs) prevent supine sleep, although there is a paucity of guidance to help clinicians decide when to use PMDs for their patients. In order for PMDs to treat OSA effectively, patients must experience respiratory events in the supine sleeping position consistently from night to night and must have a low nonsupine apnea and hypopnea index (AHINS).
OBJECTIVES
To document the repeatability of traditionally defined supine predominant OSA on consecutive polysomnography, to determine whether the consistency of the supine-predominant phenotype can be improved by altering the definition of it, and to determine whether a low AHINS is repeatable from night to night.
METHODS
We recruited 75 patients for polysomnography on two separate nights. Patients were classified as having supine OSA on each night on the basis of traditional and novel definitions, and the classification systems used were compared on the basis of agreement from night to night.
MEASUREMENTS AND MAIN RESULTS
The definition of supine OSA with the highest level of agreement from night to night incorporates a supine AHI (AHIS) to AHINS ratio ≥4:1. In addition, agreement exists for males, but there is poor agreement for female patients, regardless of the definition applied. An AHINS <10 events/hour is highly repeatable from night to night.
CONCLUSIONS
Males with an AHIS:AHINS ratio ≥4:1 and an AHINS <10 events/hour represent a consistent supine-predominant OSA phenotype from night to night. This patient group is likely to benefit from treatment with PMD.
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影响因子：
3.3
作者：
Wellman, Andrew;Edwards, Bradley A.;White, David P.
通讯作者：
White, David P.
DOI：
10.1164/ajrccm.152.2.7633734
发表时间：
1995-08-01
影响因子：
24.7
作者：
POPOVIC, RM;WHITE, DP
通讯作者：
WHITE, DP
正常呼吸范围内的肺、胸壁和整个呼吸系统的阻力和弹性。
DOI：
10.1164/ajrccm/145.1.110
发表时间：
1992
期刊：
The American review of respiratory disease
影响因子：
--
作者：
Barnas,GM;Campbell,DN;Mackenzie,CF;Mendham,JE;Fahy,BG;Runcie,CJ;Mendham,GE
通讯作者：
Mendham,GE
DOI：
10.1164/rccm.200412-1750oc
发表时间：
2005-11-15
影响因子：
24.7
作者：
Fenik, VB;Davies, RO;Kubin, L
通讯作者：
Kubin, L
DOI：
10.1164/ajrccm/147.4.887
发表时间：
1993-04-01
期刊：
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子：
--
作者：
KRIBBS, NB;PACK, AI;DINGES, DF
通讯作者：
DINGES, DF