Objective and Subjective Sleep Measures Are Related to Suicidal Ideation and Are Transdiagnostic Features of Major Depressive Disorder and Social Anxiety Disorder.

Objective and Subjective Sleep Measures Are Related to Suicidal Ideation and Are Transdiagnostic Features of Major Depressive Disorder and Social Anxiety Disorder.
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DOI:
10.3390/brainsci13020288
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发表时间:
2023-02-08
期刊:
影响因子:
3.3
通讯作者:
Burgess, Helen J.
Burgess, Helen J.
中科院分区:
医学4区
文献类型:
--
作者:
Klumpp, Heide;Chang, Fini;Bauer, Brian W.;Burgess, Helen J.

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自杀是一个主要的公共卫生问题,先前对抑郁症和焦虑症的研究表明,睡眠问题是自杀意念(SI)的危险因素。然而,对社交焦虑障碍(SAD)中的睡眠和SI知之甚少,尽管SAD普遍存在。因此,本研究包括重度抑郁症(MDD)(无合并SAD)(n = 26)和SAD(无合并MDD)(n = 41)参与者。腕动计用于估计睡眠时间、入睡后觉醒和睡眠效率;睡眠质量通过自我报告进行评估。自我报告也被用来检查SI。这些措施提交独立的t检验和多元回归分析。t检验结果显示,睡眠和SI在MDD和SAD组之间没有差异。多元回归分析结果显示,当考虑症状严重程度和年龄时,睡眠持续时间较短和睡眠质量较差与SI较大相关。事后部分相关分析显示,这些睡眠SI的关系仍然显着控制后的症状严重程度和年龄。初步研究结果表明,睡眠和SI可能是MDD和SAD的跨诊断特征。不同的睡眠SI关系的证据是一致的,以前的报告表明,睡眠困难有助于SI。总之,改善睡眠时间和睡眠质量可以降低SI的风险。
Suicide is a major public health problem and previous studies in major depression and anxiety show problematic sleep is a risk factor for suicidal ideation (SI). However, less is known about sleep and SI in social anxiety disorder (SAD), despite the pervasiveness of SAD. Therefore, the current study comprised participants with major depressive disorder (MDD) (without comorbid SAD) (n = 26) and participants with SAD (without comorbid MDD) (n = 41). Wrist actigraphy was used to estimate sleep duration, wake after sleep onset, and sleep efficiency; sleep quality was evaluated with self-report. Self-report was also used to examine SI. These measures were submitted to independent t-tests and multiple regression analysis. t-test results revealed sleep and SI did not differ between MDD and SAD groups. Multiple regression results showed shorter sleep duration and worse sleep quality related to greater SI when taking symptom severity and age into account. Post-hoc partial correlational analysis showed these sleep–SI relationships remained significant after controlling for symptom severity and age. Preliminary findings indicate sleep and SI may be transdiagnostic features of MDD and SAD. Evidence of distinct sleep–SI relationships are consistent with previous reports showing that sleep difficulties contribute to SI. Altogether, improving sleep duration and sleep quality may reduce the risk of SI.
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