Associations of childhood diet quality scores with arterial stiffness and carotid artery intima-media thickness in adolescence/early adulthood: findings from the ALSPAC cohort.
Associations of childhood diet quality scores with arterial stiffness and carotid artery intima-media thickness in adolescence/early adulthood: findings from the ALSPAC cohort.
复制标题
DOI：
10.1017/s0007114523002763
复制
发表时间：
2024-02-28
影响因子：
3.6
通讯作者：
Taylor, Caroline M.
中科院分区：
文献类型：
--
作者：
Buckland, Genevieve;Northstone, Kate;Emmett, Pauline M.;Taylor, Caroline M.
关键词：
这项研究探讨了儿童饮食质量与青春期/成年早期动脉硬度和厚度之间的关系。参与者来自雅芳父母和儿童纵向研究 (ALSPAC)，提供 7、10 和 13 岁时的饮食数据以及 17 和/或 24 岁时的脉搏波速度 (PWV) 和颈动脉内膜中层厚度 (cIMT)。饮食质量 (DQ) 使用五个评分进行评估：儿童地中海式饮食 (C-rMED) Z 评分、儿童饮食炎症 Z 评分 (C-DIS)、DASH 饮食 Z 评分、反映英国饮食指南的儿童饮食指南 (C-EWG) Z 评分和数据驱动的致肥 Z 评分。调整后的回归模型检查了 7-13 岁时的 DQ 评分与 17 和 24 岁时的 PWV 和 cIMT 之间的关联。在调整后的模型中，7 年和 10 年的高肥胖 Z 分数与低肥胖 Z 分数与 17 年较高的 PWV 相关：分别为 β 0.07 (95 % CI 0.01, 0.13) 和 β 0.10 (95 % CI 0.04, 0.16)。 7 年时的高 C-rMED Z 分数与低 C-rMED Z 分数与 17 岁时的较低 PWV 相关（β -0.07；95 % CI -0.14，-0.01）。 10 年时的高（抗炎性更强）与低的 C-DIS Z 分数与 17 岁时较低的 PWV 相关：β -0.06 (95 % CI -0.12, -0.01)。没有观察到其他关联。总之，儿童期（7-10 岁）的肥胖饮食模式与动脉僵硬度增加有关，而地中海式饮食和抗炎饮食则与青春期动脉僵硬度降低有关。这凸显了在生命早期建立健康饮食习惯以防止血管损伤的重要性。
This study examined the relationship between childhood diet quality and arterial stiffness and thickness during adolescence/early adulthood. Participants were from the Avon Longitudinal Study of Parents and Children (ALSPAC) with dietary data at ages 7, 10 and 13 years and pulse wave velocity (PWV) and carotid intima-media thickness (cIMT) at ages 17 and/or 24 years. Diet quality (DQ) was assessed using five scores: a children’s Mediterranean-style diet (C-rMED) Z-score, a children’s Dietary Inflammatory Z-score (C-DIS), a DASH diet Z-score, a children’s Eatwell Guide (C-EWG) Z-score reflecting UK dietary guidelines and a data-driven obesogenic Z-score. Adjusted regression models examined the associations between DQ scores at 7–13 years and PWV and cIMT at 17 and 24 years. In adjusted models, a high v. low Obesogenic Z-score at 7 and 10 years was associated with higher PWV at 17: β 0.07 (95 % CI 0.01, 0.13) and β 0.10 (95 % CI 0.04, 0.16), respectively. A high v. low C-rMED Z-score at 7 years was associated with lower PWV at 17 (β −0.07; 95 % CI −0.14, −0.01). A high (more anti-inflammatory) vs low C-DIS Z-score at 10 years was associated with a lower PWV at 17 years: β −0.06 (95 % CI −0.12, −0.01). No other associations were observed. In conclusion, an Obesogenic dietary pattern in childhood (7–10 years) was related to increased arterial stiffness, while Mediterranean-style and anti-inflammatory diets were related to decreased arterial stiffness in adolescence. This highlights the importance of establishing healthy dietary habits early in life to protect against vascular damage.
影响因子：
3
作者：
Liese AD;Couch SC;The NS;Crandell JL;Lawrence JM;Crume TL;Mayer-Davis EJ;Zhong VW;Urbina EM
通讯作者：
Urbina EM
影响因子：
4.5
作者：
通讯作者：
--