Gender variations in neonatal and early infant mortality in India and Pakistan: a secondary analysis from the Global Network Maternal Newborn Health Registry.
Gender variations in neonatal and early infant mortality in India and Pakistan: a secondary analysis from the Global Network Maternal Newborn Health Registry.
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印度和巴基斯坦新生儿和婴儿早期死亡率的性别差异：全球新生儿卫生注册表的二次分析。
DOI：
10.1186/s12978-020-01028-0
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发表时间：
2020-12-17
影响因子：
3.4
通讯作者：
Derman RJ
中科院分区：
文献类型：
--
作者：
Aghai ZH;Goudar SS;Patel A;Saleem S;Dhaded SM;Kavi A;Lalakia P;Naqvi F;Hibberd PL;McClure EM;Nolen TL;Iyer P;Goldenberg RL;Derman RJ
利用产妇新生儿健康登记处的全球网络数据，确定南亚新生儿死亡率、死胎和围产儿死亡率的性别差异。这项研究是对从全球网络的三个南亚站点预期收集的数据进行的二次分析。比较男婴和女婴的人口学、临床特征、死产率、早期新生儿死亡率(1~7天)、晚期新生儿死亡率(8~28天)、29~42天死亡率和出生后住院婴儿数。2010至2018年间，来自两个印度地点和一个巴基斯坦地点的297 509名新生儿[154,790名男性(52.03%)和142,719名女性(47.97%)]被纳入分析[活产288,859名(97.1%)和死产8,648名(2.9%)]。男婴的新生儿死亡率(33.2‰活产)明显高于女婴(27.4‰，p <； 0.001)。男性的死产率(31.0比26.9/1000)和早期新生儿死亡率(27.1比21.6/1000活产)也较高。然而，两组的晚期新生儿死亡率(6.3比5.9/1000活产儿)和29-42天的死亡率(2.1比1.9/1000活产儿)没有显著差异。出生后42天内住院的男婴比女婴多(活产儿1.8‰比1.3‰，p <； 0.001)。男婴的死产风险和早期新生儿死亡率高于女婴。然而，7日龄后的死亡率没有性别差异。我们的结果强调了将新生儿死亡率分为新生儿早期和晚期的重要性，以更好地了解性别对新生儿死亡率的影响。这项研究的信息将有助于制定战略和确定措施，以减少特定性别死亡率的差异。
To determine the gender differences in neonatal mortality, stillbirths, and perinatal mortality in south Asia using the Global Network data from the Maternal Newborn Health Registry. This study is a secondary analysis of prospectively collected data from the three south Asian sites of the Global Network. The maternal and neonatal demographic, clinical characteristics, rates of stillbirths, early neonatal mortality (1–7 days), late neonatal mortality (8–28 days), mortality between 29–42 days and the number of infants hospitalized after birth were compared between the male and female infants. Between 2010 and 2018, 297,509 births [154,790 males (52.03%) and 142,719 females (47.97%)] from two Indian sites and one Pakistani site were included in the analysis [288,859 live births (97.1%) and 8,648 stillbirths (2.9%)]. The neonatal mortality rate was significantly higher in male infants (33.2/1,000 live births) compared to their female counterparts (27.4/1,000, p < 0.001). The rates of stillbirths (31.0 vs. 26.9/1000 births) and early neonatal mortality (27.1 vs 21.6/1000 live births) were also higher in males. However, there were no significant differences in late neonatal mortality (6.3 vs. 5.9/1000 live births) and mortality between 29–42 days (2.1 vs. 1.9/1000 live births) between the two groups. More male infants were hospitalized within 42 days after birth (1.8/1000 vs. 1.3/1000 live births, p < 0.001) than females. The risks of stillbirths, and early neonatal mortality were higher among male infants than their female counterparts. However, there was no gender difference in mortality after 7 days of age. Our results highlight the importance of stratifying neonatal mortality into early and late neonatal period to better understand the impact of gender on neonatal mortality. The information from this study will help in developing strategies and identifying measures that can reduce differences in sex-specific mortality.
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影响因子：
3.1
作者：
Hou L;Wang X;Li G;Zou L;Chen Y;Zhang W
通讯作者：
Zhang W
DOI：
10.1080/14767058.2016.1210597
发表时间：
2017-06-01
影响因子：
1.8
作者：
Condo, Valentina;Cipriani, Sonia;Mosca, Fabio
通讯作者：
Mosca, Fabio
影响因子：
2
作者：
Short, Vanessa L.;Geller, Stacie E.;Derman, Richard J.
通讯作者：
Derman, Richard J.
DOI：
10.1111/1471-0528.15585
发表时间：
2019-05-01
影响因子：
5.8
作者：
Parks, S.;Hoffman, M. K.;Derman, R. J.
通讯作者：
Derman, R. J.
DOI：
10.1073/pnas.1812593116
发表时间：
2019-05-07
影响因子：
11.1
作者：
Chao, Fengqing;Gerland, Patrick;Alkema, Leontine
通讯作者：
Alkema, Leontine