Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis.
Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis.
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超临界流体色谱在草药分析中的进展
DOI：
10.3390/molecules27134159
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发表时间：
2022-06-29
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影响因子：
--
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中科院分区：
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草药成分分析面临的最大挑战在于其多样性和复杂性。因此，用于多成分分离以及定性和定量分析的高效分析工具至关重要。近年来，各种新兴的分析技术为复杂成分分析提供了重要支持，在选择性、灵敏度和快速分析方面取得了突破。在这些技术中，超临界流体色谱（SFC）因其柱效高和环保而备受关注。SFC可用于分析多种化合物，包括非极性和极性化合物，使其成为一个突出的分析平台。本文综述了SFC在草药天然产物分离和测定中的适用性。通过固定相和流动相的选择和优化，扩大了应用范围。我们还重点关注了二维SFC分析。本文为草药分析的SFC方法开发提供了新的见解。
The greatest challenge in the analysis of herbal components lies in their variety and complexity. Therefore, efficient analytical tools for the separation and qualitative and quantitative analysis of multi-components are essential. In recent years, various emerging analytical techniques have offered significant support for complicated component analysis, with breakthroughs in selectivity, sensitivity, and rapid analysis. Among these techniques, supercritical fluid chromatography (SFC) has attracted much attention because of its high column efficiency and environmental protection. SFC can be used to analyze a wide range of compounds, including non-polar and polar compounds, making it a prominent analytical platform. The applicability of SFC for the separation and determination of natural products in herbal medicines is overviewed in this article. The range of applications was expanded through the selection and optimization of stationary phases and mobile phases. We also focus on the two-dimensional SFC analysis. This paper provides new insight into SFC method development for herbal medicine analysis.
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影响因子：
4.1
作者：
Chou, Fu-Min;Wang, Wei-Ting;Wei, Guor-Tzo
通讯作者：
Wei, Guor-Tzo
影响因子：
4.1
作者：
Ashraf-Khorassani, M.;Taylor, L. T.;Seest, E.
通讯作者：
Seest, E.
影响因子：
4.1
作者：
da Silva, Carla G. A.;Collins, Carol H.;West, Caroline
通讯作者：
West, Caroline
影响因子：
2.9
作者：
Donato, Paola;Giuffrida, Daniele;Mondello, Luigi
通讯作者：
Mondello, Luigi
影响因子：
8.8
作者：
Giuffrida, Daniele;Zoccali, Mariosimone;Mondello, Luigi
通讯作者：
Mondello, Luigi