MR imaging of iliofemoral peripheral vascular calcifications using proton density-weighted, in-phase three-dimensional stack-of-stars gradient echo.
MR imaging of iliofemoral peripheral vascular calcifications using proton density-weighted, in-phase three-dimensional stack-of-stars gradient echo.
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DOI：
10.1002/mrm.26295
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发表时间：
2017-06
影响因子：
3.3
通讯作者：
Edelman, Robert R.
中科院分区：
文献类型：
--
作者：
Botelho, Marcos P. Ferreira;Koktzoglou, Ioannis;Collins, Jeremy D.;Giri, Shivraman;Carr, James C.;Gupta, NavYash;Edelman, Robert R.
血管钙化的存在有助于确定介入血管手术的经皮通路，并对未来心血管事件具有预后价值。与CT不同，标准的MRI技术对血管钙化不敏感。在这项前瞻性研究中，我们测试了质子密度加权的同相（PDIP）三维星堆梯度回波脉冲序列，在1.5特斯拉和3特斯拉的各向同性空间分辨率约为1 mm3，以检测髂-股周围血管钙化，并将mr确定的病变体积与CT血管造影相关联。这项研究得到了机构审查委员会的批准。应用原型PDIP叠星脉冲序列对12例行CT血管造影的髂股周围血管钙化患者进行了研究。除假体或支架附近的节段外，所有受试者的血管钙化都很明显。钙化的位置、大小和形状与CTA相似。定量分析显示MR和ct测量的钙化体积之间具有良好的相关性（r2 = 0.84, p<0.0001）。在一个被试中，三个脉冲序列进行了比较，PDIP星图的表现优于笛卡尔三维梯度回波和PETRA。在这项初步研究中，具有高空间分辨率的PDIP 3D星堆梯度回波脉冲序列提供了出色的图像质量，并准确地描述了髂股血管钙化的位置和体积。
The presence of vascular calcifications helps to determine percutaneous access for interventional vascular procedures and has prognostic value for future cardiovascular events. Unlike CT, standard MRI techniques are insensitive to vascular calcifications. In this prospective study, we tested a proton density-weighted, in-phase (PDIP) 3D stack-of-stars gradient-echo pulse sequence with approximately 1 mm3 isotropic spatial resolution at 1.5 Tesla and 3 Tesla to detect ilio-femoral peripheral vascular calcifications and correlated MR-determined lesion volumes with CT angiography. The study was approved by the Institutional Review Board. The prototype PDIP stack-of-stars pulse sequence was applied in 12 patients with ilio-femoral peripheral vascular calcifications who had undergone CT angiography. Vascular calcifications were well visualized in all subjects, excluding segments near prostheses or stents. The location, size and shape of the calcifications were similar to CTA. Quantitative analysis showed excellent correlation (r2 = 0.84, p<0.0001) between MR- and CT-based measures of calcification volume. In one subject in whom three pulse sequences were compared, PDIP stack-of-stars outperformed Cartesian 3D gradient-echo and PETRA. In this pilot study, a PDIP 3D stack-of-stars gradient-echo pulse sequence with high spatial resolution provided excellent image quality and accurately depicted the location and volume of ilio-femoral vascular calcifications.
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影响因子：
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