Clinical outcome 5 years after attempted percutaneous transluminal coronary angioplasty in 427 patients.
Clinical outcome 5 years after attempted percutaneous transluminal coronary angioplasty in 427 patients.
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427 名患者尝试经皮腔内冠状动脉成形术 5 年后的临床结果。
DOI：
10.1161/01.cir.77.4.820
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发表时间：
1988
期刊：
影响因子：
37.8
通讯作者：
W. S. Weintraub
中科院分区：
文献类型：
--
作者：
J D Talley;J. W. Hurst;S. B. King;J. S. Douglas;G. Roubin;A. Gruentzig;H. Anderson;W. S. Weintraub
本研究对1981年接受经皮冠状动脉腔内成形术(PTCA)的427例患者的5年临床情况进行了分析。平均年龄54±10岁(+/-1 SD)。61%的人有不稳定心绞痛，23%的人有心肌梗死史，86%的人有单支血管疾病，92%的人左心功能正常。67%的患者有左前降支狭窄。84%的患者血管造影术成功。9.6%的患者需要冠状动脉搭桥手术，5.9%的患者需要紧急手术。没有住院死亡病例。术后5年随访100%完成。晚期死亡15例(存活率96.3+/-1.0%)，其中心脏死亡7例(心脏存活率98.1+/-0.7%)。发生心肌梗死24例(94%免于心肌梗死)，63例需要冠状动脉搭桥手术(84%免于搭桥手术)，365例(85%)在随访时无症状。在5年时，83名患者(20%)需要额外的PTCA。162例患者存在不稳定型心绞痛和冠状动脉近端左前降支狭窄。总存活率和心脏存活率分别为94.4+/-1.8%和98.1+/-1.1%。该人群5年来的良好存活率和低事件发生率支持了PTCA对于有症状的心绞痛、单支血管疾病和左心功能正常的患者是安全有效的概念。
This study was performed to define the 5 year clinical status of 427 patients who underwent percutaneous transluminal coronary angioplasty (PTCA) in 1981. Their mean age was 54 +/- 10 years (+/- 1 SD). Sixty-one percent had unstable angina, 23% had prior myocardial infarction, 86% had one-vessel disease, and 92% had normal left ventricular function. Sixty-seven percent of patients had left anterior descending artery stenosis. Angiographic success was achieved in 84% of patients. Coronary bypass surgery was required in 9.6% of patients, in 5.9% as an emergency procedure. There were no in-hospital deaths. Follow-up at 5 years was 100% complete. There were 15 late deaths (96.3 +/- 1.0% survival), including seven of cardiac cause (98.1 +/- 0.7% cardiac survival). Myocardial infarction occurred in 24 patients (94% freedom from myocardial infarction), coronary bypass surgery was required in 63 (84% freedom from bypass surgery), and 365 patients (85%) were asymptomatic at follow-up. At 5 years, 83 patients (20%) had required an additional PTCA. Unstable angina pectoris and proximal left anterior descending coronary artery stenoses were present in 162 patients. The overall survival and cardiac survival in this subset was 94.4 +/- 1.8% and 98.1 +/- 1.1%, respectively. The excellent survival and low event rates over 5 years in this population support the concept that PTCA is safe and effective for patients with symptomatic angina pectoris, single-vessel disease, and normal left ventricular function.
适合经皮冠状动脉腔内成形术的单支血管病变患者的自然史。
DOI：
10.1016/0002-9149(83)90112-1
发表时间：
1983
期刊：
The American journal of cardiology
影响因子：
--
作者：
Hlatky,MA;Califf,RM;Kong,Y;HarrellJr,FE;Rosati,RA
通讯作者：
Rosati,RA
致命性心肌梗死中急性左前降支冠状动脉近端病变的优势：一项临床病理学研究。
DOI：
10.1016/0002-9149(81)90246-0
发表时间：
1981
期刊：
The American journal of cardiology
影响因子：
--
作者：
Schuster,EH;Griffith,LS;Bulkley,BH
通讯作者：
Bulkley,BH