Application of the T-matrix method to determine the structure of spheroidal cell nuclei with angle-resolved light scattering.
Application of the T-matrix method to determine the structure of spheroidal cell nuclei with angle-resolved light scattering.
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DOI:
10.1364/ol.33.002452
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发表时间:
2008-11-01
期刊:
影响因子:
3.6
通讯作者:
Wax A
中科院分区:
文献类型:
--
作者:
Giacomelli MG;Chalut KJ;Ostrander JH;Wax A
We demonstrate an inverse light-scattering analysis procedure based on using the T-matrix method as a light-scattering model. We measure light scattered by in vitro cell monolayers using angle-resolved low-coherence interferometry (a/LCI) and compare the data to predictions of the T-matrix theory. The comparison yields measurements of the equal volume diameter and aspect ratio of the spheroid cell nuclei with accuracy comparable to quantitative image analysis of fixed and stained samples. These improvements represent a significant upgrade for the a/LCI technique, expanding both the range of tissue in which it is applicable and potentially increasing its value as a diagnostic tool.
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影响因子:
1.9
作者:
Duncan, Donald D.;Thomas, Michael E.
通讯作者:
Thomas, Michael E.
DOI:
10.1016/0022-4073(96)00002-7
发表时间:
1996-05-01
影响因子:
2.3
作者:
Mishchenko, MI;Travis, LD;Mackowski, DW
通讯作者:
Mackowski, DW
DOI:
10.1364/josaa.25.001866
发表时间:
2008-08
期刊:
Journal of the Optical Society of America. A, Optics, image science, and vision
影响因子:
--
作者:
Chalut KJ;Giacomelli MG;Wax A
通讯作者:
Wax A
影响因子:
3.8
作者:
Pyhtila, JW;Graf, RN;Wax, A
通讯作者:
Wax, A
影响因子:
1.9
作者:
Nilsson, AMK;Alsholm, P;Andersson-Engels, S
通讯作者:
Andersson-Engels, S