Evaluation of spiral acquisition variants for functional imaging of human superior colliculus at 3T field strength.
Evaluation of spiral acquisition variants for functional imaging of human superior colliculus at 3T field strength.
复制标题
评估3T场强度在3T场强的人类上丘的功能成像的螺旋习得变体。
DOI：
10.1002/mrm.26845
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发表时间：
2018-04
影响因子：
3.3
通讯作者：
Ress D
中科院分区：
文献类型：
--
作者：
Singh V;Pfeuffer J;Zhao T;Ress D
人类皮层下脑结构的高分辨率功能磁共振成像是具有挑战性的，因为它们在颅骨中的位置较深，并且它们对强刺激的BOLD反应相对较弱。大脑皮层下区域的磁共振成像数据表现出低信噪比和低功能对比噪声比（CNR）。为了克服这些挑战，这项工作评估使用双回波螺旋变体，联合收割机向外和向内的轨迹。具体地，评估输入-输入、输入-输出和输出-输出组合。为了完整性，还评价了单回波螺旋进入和并行接收加速回波平面成像序列。序列评价是基于视网膜定位预定义的感兴趣区域内的功能对比噪声比的比较。选择上级丘（SC）作为样本皮层下脑区，因为它表现出强烈的视觉反应。所有序列相对于单回波螺旋轨迹进行比较，以建立会话内参考。在SC中，双回波输出在CNR中优于参考轨迹55%，而所有其他轨迹的性能与参考轨迹相似。这些序列也在早期视觉皮层中进行了比较。在这里，双回波螺旋输出和输入输出的性能均优于参考值约25%。双回波螺旋变体为SC和皮质的高分辨率成像提供了改进的CNR性能。
High-resolution functional magnetic resonance imaging of human subcortical brain structures is challenging because of their deep location in the cranium, and their comparatively weak BOLD responses to strong stimuli. Magnetic resonance imaging data for subcortical brain regions exhibit both low signal-to-noise ratio and low functional contrast-to-noise ratio (CNR). To overcome these challenges, this work evaluates the use of dual-echo spiral variants that combine outward and inward trajectories. Specifically, in-in, in-out, and out-out combinations are evaluated. For completeness, single-echo spiral-in and parallel-receive-accelerated echo-planar-imaging sequences are also evaluated. Sequence evaluation was based on comparison of functional contrast-to-noise ratio within retinotopically predefined regions of interest. Superior colliculus (SC) was chosen as sample subcortical brain region because it exhibits a strong visual response. All sequences were compared relative to a single-echo spiral-out trajectory to establish a within-session reference. In SC, the dual-echo out-out outperformed the reference trajectory by 55% in CNR, while all other trajectories had performance similar to the reference. The sequences were also compared in early visual cortex. Here, both dual-echo spiral out-out and in-out outperformed the reference by ~25%. Dual-echo spiral variants offer improved CNR performance for high-resolution imaging for both SC and cortex.
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影响因子：
5.7
作者：
Glover, Gary H.
通讯作者：
Glover, Gary H.
影响因子：
3.3
作者：
Glover, GH;Thomason, ME
通讯作者：
Thomason, ME
影响因子：
3.3
作者：
Krüger, G;Glover, GH
通讯作者：
Glover, GH
影响因子：
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DuBois, RM;Cohen, MS
通讯作者：
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影响因子：
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作者：
Ress D;Chandrasekaran B
通讯作者：
Chandrasekaran B