Chinese Herbal Compounds for the Prevention and Treatment of Atherosclerosis: Experimental Evidence and Mechanisms.
Chinese Herbal Compounds for the Prevention and Treatment of Atherosclerosis: Experimental Evidence and Mechanisms.
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DOI：
10.1155/2015/752610
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Fan D
中科院分区：
文献类型：
--
作者：
Liu Q;Li J;Hartstone-Rose A;Wang J;Li J;Janicki JS;Fan D
动脉粥样硬化是全球残疾和死亡的主要原因。对该疾病的研究已经导致了许多关于动脉粥样硬化病变形成的病理生理学和由此产生的并发症如心肌梗死和中风的令人信服的假设。中草药在中国和亚洲其他国家已被广泛用于治疗心血管疾病数百年，但中草药在预防和治疗动脉粥样硬化中的作用机制尚未得到充分研究。本文简要介绍了动脉粥样硬化的发生机制，并总结了近年来有关抗动脉粥样硬化中草药化合物的有效性及其作用机制的研究，试图在中医药与细胞分子心血管医学之间架起一座桥梁。
Atherosclerosis is a leading cause of disability and death worldwide. Research into the disease has led to many compelling hypotheses regarding the pathophysiology of atherosclerotic lesion formation and the resulting complications such as myocardial infarction and stroke. Herbal medicine has been widely used in China as well as other Asian countries for the treatment of cardiovascular diseases for hundreds of years; however, the mechanisms of action of Chinese herbal medicine in the prevention and treatment of atherosclerosis have not been well studied. In this review, we briefly describe the mechanisms of atherogenesis and then summarize the research that has been performed in recent years regarding the effectiveness and mechanisms of antiatherogenic Chinese herbal compounds in an attempt to build a bridge between traditional Chinese medicine and cellular and molecular cardiovascular medicine.
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DOI：
10.1248/yakushi.125.587
发表时间：
2005-07-01
影响因子：
0.3
作者：
Duan, WG;Yu, Y;Zhang, LY
通讯作者：
Zhang, LY
影响因子：
7.2
作者：
Amrani, Souliman;Harnafi, Hicham;Bravo, Elena
通讯作者：
Bravo, Elena
影响因子：
7.5
作者：
Chen, Shih Chung;Lin, Yun Lian;Cheng, Jing Jy
通讯作者：
Cheng, Jing Jy
影响因子：
3.3
作者：
Choi, Deok Ho;Lee, Yun Jung;Lee, Ho Sub
通讯作者：
Lee, Ho Sub
影响因子：
7.3
作者：
Chen, YH;Lin, SJ;Chen, YL
通讯作者：
Chen, YL