The relationship between diabetes distress and clinical depression with glycemic control among patients with type 2 diabetes.

The relationship between diabetes distress and clinical depression with glycemic control among patients with type 2 diabetes.
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DOI:
10.2337/dc09-2175
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发表时间:
2010-05
期刊:
影响因子:
16.2
通讯作者:
Strycker LA
Strycker LA
中科院分区:
医学1区
文献类型:
--
作者:
Fisher L;Glasgow RE;Strycker LA

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为了澄清先前的发现,糖尿病困扰与血糖控制和自我管理有关,而抑郁症的措施则没有,使用二元和连续的抑郁症措施。463例2型患者完成了糖尿病痛苦(糖尿病痛苦量表[DDS])和临床抑郁(患者健康问卷8 [PHQ 8])的测量。PHQ 8用作二元(≥10)或连续变量。因变量为A1 C、饮食、体力活动(PA)和药物依从性(MA)。纳入二元或连续PHQ 8评分在任何方程中均无差异。DDS与A1 C和PA显著相关,而PHQ 8则不相关; DDS和PHQ 8均与饮食和MA显著且独立相关。抑郁症和血糖控制之间缺乏关联并不是因为使用了抑郁症的二元测量。研究结果进一步阐明了痛苦和A1 C之间的重要联系。
To clarify previous findings that diabetes distress is related to glycemic control and self-management whereas measures of depression are not, using both binary and continuous measures of depression. Four hundred and sixty-three type 2 patients completed measures of diabetes distress (Diabetes Distress Scale [DDS]) and clinical depression (Patient Health Questionnaire 8 [PHQ8]). PHQ8 was employed as either a binary (≥10) or continuous variable. Dependent variables were A1C, diet, physical activity (PA), and medication adherence (MA). The inclusion of a binary or continuous PHQ8 score yielded no differences in any equation. DDS was significantly associated with A1C and PA, whereas PHQ8 was not; both DDS and PHQ8 were significantly and independently associated with diet and MA. The lack of association between depression and glycemic control is not due to the use of a binary measure of depression. Findings further clarify the significant association between distress and A1C.
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