Type VI secretion systems in plant-associated bacteria.

Type VI secretion systems in plant-associated bacteria.
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DOI:
10.1111/1462-2920.13956
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发表时间:
2018-01
影响因子:
5.1
通讯作者:
Filloux A
Filloux A
中科院分区:
生物学2区
文献类型:
--
作者:
Bernal P;Llamas MA;Filloux A

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VI型分泌系统(T6 SS)是一种细菌纳米机器,用于将效应子注入原核或真核细胞,因此参与宿主操纵和细菌间竞争。T6 SS广泛存在于革兰氏阴性菌中,主要在变形杆菌门内。这种分泌系统通常存在于真菌和病原性植物相关细菌中。植物细菌T6 SS簇的系统发育分析表明,它们分布在前面描述的五个主要分支(组1-5)。该系统的均匀分布在植物和病原性植物细菌中表明,T6 SS在植物中提供了适应性和定殖优势,并且T6 SS的作用不限于毒力。本文综述了T6 SS在植物相关细菌中的遗传和生物学作用,突出了在机制和功能方面的显着多样性。
The type VI secretion system (T6SS) is a bacterial nanomachine used to inject effectors into prokaryotic or eukaryotic cells and is thus involved in both host manipulation and interbacterial competition. The T6SS is widespread among Gram‐negative bacteria, mostly within the Proteobacterium Phylum. This secretion system is commonly found in commensal and pathogenic plant‐associated bacteria. Phylogenetic analysis of phytobacterial T6SS clusters shows that they are distributed in the five main clades previously described (group 1–5). The even distribution of the system among commensal and pathogenic phytobacteria suggests that the T6SS provides fitness and colonization advantages in planta and that the role of the T6SS is not restricted to virulence. This manuscript reviews the phylogeny and biological roles of the T6SS in plant‐associated bacteria, highlighting a remarkable diversity both in terms of mechanism and function.
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