Clinical application of plasma thermograms. Utility, practical approaches and considerations.
Clinical application of plasma thermograms. Utility, practical approaches and considerations.
复制标题
DOI:
10.1016/j.ymeth.2014.10.030
复制
发表时间:
2015-04
期刊:
影响因子:
4.8
通讯作者:
Chaires, Jonathan B.
中科院分区:
文献类型:
--
作者:
Garbett, Nichola C.;Mekmaysy, Chongkham S.;DeLeeuw, Lynn;Chaires, Jonathan B.
Differential scanning calorimetry (DSC) studies of blood plasma are part of an emerging area of the clinical application of DSC to biofluid analysis. DSC analysis of plasma from healthy individuals and patients with various diseases has revealed changes in the thermal profiles of the major plasma proteins associated with the clinical status of the patient. The sensitivity of DSC to the concentration of proteins, their interactions with other proteins or ligands, or their covalent modifications underlies the potential utility of DSC analysis. A growing body of literature has demonstrated the versatility and performance of clinical DSC analysis across a range of biofluids and in a number of disease settings. The principles, practice and challenges of DSC analysis of plasma are described in this article.
登录
查看更多内容
影响因子:
2.9
作者:
BRANDTS, JF;LIN, LN
通讯作者:
LIN, LN
影响因子:
4.8
作者:
Chagovetz, Alexis A.;Quinn, Colette;Jensen, Randy L.
通讯作者:
Jensen, Randy L.
影响因子:
3.5
作者:
Zapf, Istvan;Fekecs, Tamas;Lorinczy, Denes
通讯作者:
Lorinczy, Denes
DOI:
10.1016/j.bbagen.2013.05.007
发表时间:
2013-10
期刊:
Biochimica et biophysica acta
影响因子:
--
作者:
Garbett NC;Merchant ML;Chaires JB;Klein JB
通讯作者:
Klein JB
影响因子:
3.5
作者:
LODDER, RA;HIEFTJE, GM
通讯作者:
HIEFTJE, GM