chiral separation by electronkinetic chromatography while bile salt micelles
chiral separation by electronkinetic chromatography while bile salt micelles
复制标题
通过电子动力色谱法进行手性分离，而胆汁盐胶束
DOI：
10.1016/s0021-9673(01)84309-0
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发表时间：
1989
影响因子：
4.1
通讯作者：
Yosuke Miyashita
中科院分区：
文献类型：
--
作者：
S. Terabe;M. Shibata;Yosuke Miyashita
采用不同的胆汁盐溶液进行胶束电动色谱。许多外消旋丹磺酰化氨基酸被成功地拆分，特别是在酸性条件下用牛磺脱氧胆酸盐溶液。由溶质、胶束和甲醇的保留时间测定了外消旋氨基酸的表观容量因子和表观分离因子。讨论了荷电溶质的保留参数和电渗对拆分的影响，并提出了可能的手性分离机理。
Various bile salt solutions were employed for micellar electrokinetic chromatography. Many racemic dansylated amino acids were successfully resolved, especially with a taurodeoxycholate solution under acidic conditions. Apparent capacity factors and apparent separation factors of racemic Dns-amino acids were determined from retention times of the solute, the micelle and methanol. Retention parameters of charged solutes and the effect of electroosmosis on resolution are discussed and a possible chiral separation mechanism is suggested.
影响因子：
7.4
作者：
R. A. Wallingford;A. Ewing
通讯作者：
R. A. Wallingford;A. Ewing