Rapid eradication of antibiotic-resistant bacteria and biofilms by MXene and near-infrared light through photothermal ablation
Rapid eradication of antibiotic-resistant bacteria and biofilms by MXene and near-infrared light through photothermal ablation
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通过光热消融,MXene 和近红外光快速消灭抗生素耐药细菌和生物膜
DOI:
10.1007/s40843-020-1451-7
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发表时间:
2020-09
期刊:
影响因子:
--
通讯作者:
Weili Hong
中科院分区:
文献类型:
--
作者:
Fan Wu;Huiling Zheng;Wenzhao Wang;Qiong Wu;Qi Zhang;Jiayu Guo;Bangzheng Pu;Xinyuan Shi;Jiebo Li;Xiangmei Chen;Weili Hong
With the development and rising of antimicrobial resistance, rapid and effective killings of bacteria are urgently needed, especially for antibiotic-resistant bacteria and bacterial biofilms that are usually hard to be treated with conventional antibiotics. Here, a rapid and broad-spectrum antibacterial strategy is demonstrated through photothermal ablation with MXene and light. Ti3C2 MXenes, when combined with 808 nm light, show significant antibacterial effects in just 20 min. The antibacterial strategy is effective to 15 bacterial species tested, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). In addition, the rapid antibacterial strategy works for MRSA biofilms, by damaging the structures as well as killing bacteria in biofilms. Furthermore, the investigation of the antibacterial mechanisms shows that Ti3C2 with light kills bacteria mainly physically through inserting/contact and photothermal effect. This work broadens the potential applications of MXene and provides a way to eradicate bacteria and biofilms physically, without the likelihood of resistance development.
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DOI:
10.1016/j.ijmm.2013.06.003
发表时间:
2013
期刊:
International journal of medical microbiology : IJMM
影响因子:
--
作者:
W. Witte
通讯作者:
W. Witte
影响因子:
12.4
作者:
Han X;Jing X;Yang D;Lin H;Wang Z;Ran H;Li P;Chen Y
通讯作者:
Chen Y
影响因子:
4.6
作者:
Rasool K;Mahmoud KA;Johnson DJ;Helal M;Berdiyorov GR;Gogotsi Y
通讯作者:
Gogotsi Y
影响因子:
22
作者:
Xingfei Wei;Teng Zhang;T. Luo
通讯作者:
Xingfei Wei;Teng Zhang;T. Luo
影响因子:
17.1
作者:
Xiang, Huijing;Lin, Han;Chen, Yu
通讯作者:
Chen, Yu