Interval-counting neurons in the anuran auditory midbrain: factors underlying diversity of interval tuning.
Interval-counting neurons in the anuran auditory midbrain: factors underlying diversity of interval tuning.
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DOI：
10.1007/s00359-010-0591-8
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发表时间：
2011-01
影响因子：
2.1
通讯作者：
Edwards, Christofer J.
中科院分区：
文献类型：
--
作者：
Rose, Gary J.;Leary, Christopher J.;Edwards, Christofer J.
Many anurans use primarily the temporal patterning of sound pulses for differentiating between spectrally similar conspecific and heterospecific call types. ‘Interval-counting’ midbrain neurons appear to be particularly important for discriminating among calls that differ in pulse repetition rate (PRR). These cells respond selectively over a particular range of PRRs and only after several pulses have occurred with the appropriate timing; single, brief sound pulses do not elicit spikes. Although most interval-counting cells examined thus far are tuned to PRRs of approximately 30 to 100 pulses/s, some are selective for slower PRRs. In addition to differences in best rate, we show that the sharpness of interval tuning varies considerably across interval-counting neurons. To further investigate the processes that determine interval tuning, we made whole-cell recordings from cells of this type. Neurons that showed temporally summating EPSPs, with little or no inhibition or activity-dependent enhancement of excitation, exhibited low-pass or band-pass tuning to slow PRRs. Neurons that were band-pass or high-pass to intermediate or fast PRRs, however, showed inhibition and rate-dependent enhancement of excitation. Surprisingly, across cells, interval tuning values calculated from membrane depolarization and spike rate measures were not significantly correlated. Neurons that showed sharp membrane depolarization-based tuning generally showed sharp spike-rate-based tuning. However, cells that showed broader membrane potential-based tuning varied considerably in their spike rate-based tuning; narrow spike-rate tuning resulted from ‘thresholding’ processes, whereby only the largest depolarizations triggered spikes. Neurons that lacked inhibition showed the greatest disparities between these two measures of interval tuning.
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影响因子：
5.3
作者：
Edwards, Christofer J.;Leary, Christopher J.;Rose, Gary J.
通讯作者：
Rose, Gary J.
DOI：
10.1007/s00359-003-0467-2
发表时间：
2003-12-01
影响因子：
2.1
作者：
Edwards, CJ;Rose, GJ
通讯作者：
Rose, GJ
影响因子：
25
作者：
Edwards, CJ;Alder, TB;Rose, GJ
通讯作者：
Rose, GJ
影响因子：
2.5
作者：
GROTHE, B
通讯作者：
GROTHE, B
影响因子：
2.5
作者：
Rose, GJ;Brenowitz, EA
通讯作者：
Brenowitz, EA