Rapid Proliferation Compensates for Defective Filamentation in Candida albicans Pathogenesis.
Rapid Proliferation Compensates for Defective Filamentation in Candida albicans Pathogenesis.
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DOI:
10.1016/j.tim.2021.08.006
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发表时间:
2021-10
影响因子:
15.9
通讯作者:
Kadosh D
中科院分区:
文献类型:
--
作者:
Kadosh D
A recent study (Dunker et al.) has shown that a Candida albicans mutant, defective for filamentation, is fully virulent due to rapid cellular proliferation in host tissues. These findings challenge the current paradigm in C. albicans pathogenesis and suggest that defects in one virulence property can be compensated for by enhancements in another.
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