Surgical Management of Gastric Cancer: A Systematic Review.
Surgical Management of Gastric Cancer: A Systematic Review.
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DOI：
10.3390/jcm10122557
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发表时间：
2021-06-09
影响因子：
3.9
通讯作者：
Mocan L
中科院分区：
文献类型：
--
作者：
Mocan L
胃癌是全球第五大常见癌症，占所有癌症死亡人数的7.7%。尽管肿瘤学领域取得了进步，放射治疗、新疗法和辅助化疗可以改善预后，但唯一具有治愈意图的治疗方法是手术，作为多模式治疗的一部分。在适当的情况下，可以采用两种概念，即胃切除术(G)前的新辅助治疗或原发性手术切除后化疗。这种方法与早期发现和更好的筛查相结合，导致胃癌的总体发病率下降。不幸的是，胃恶性肿瘤通常在局部晚期或转移期被诊断出来，此时中位总生存期仍然很低。这些病例的外科护理必须由一个多学科团队在一个大容量的中心提供。重要的手术方面，如最佳切除边缘、手术技术和淋巴结数量是影响患者预后的重要因素。胃癌手术治疗的规范化，符合患者的特点，对获得更好的治疗效果具有决定性的意义。本文就目前胃癌手术治疗的标准进行综述。
Gastric cancer is the fifth most common cancer worldwide, and it is responsible for 7.7% of all cancer deaths. Despite advances in the field of oncology, where radiotherapy, neo and adjuvant chemotherapy may improve the outcome, the only treatment with curative intent is represented by surgery as part of a multimodal therapy. Two concepts may be adopted in appropriate cases, neoadjuvant treatment before gastrectomy (G) or primary surgical resection followed by chemotherapy. Such an approach, combined with early detection and better screening, has led to a decrease in the overall incidence of gastric cancer. Unfortunately, malignant tumors of the stomach are often diagnosed in locally advanced or metastatic stages when the median overall survival remains poor. Surgical care in these cases must be provided by a multidisciplinary team in a high-volume center. Important surgical aspects such as optimum resection margins, surgical technique, and number of harvested lymph nodes are important factors for patient outcomes. The standardization of surgical treatment of gastric cancer in accordance with the patient’s profile is of decisive importance for a better outcome. This review aims to summarize the current standards in the surgical treatment of gastric cancer.
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影响因子：
50.5
作者：
Bernards, N.;Creemers, G. J.;Lemmens, V. E. P. P.
通讯作者：
Lemmens, V. E. P. P.
影响因子：
7.4
作者：
Bissolati, Massimiliano;Desio, Matteo;Orsenigo, Elena
通讯作者：
Orsenigo, Elena
影响因子：
9
作者：
Bozzetti, F;Marubini, E;Gennari, L
通讯作者：
Gennari, L
影响因子：
45.3
作者：
Hartgrink, HH;van de Velde, CJH;Sasako, M
通讯作者：
Sasako, M
影响因子：
--
作者：
Bilimoria, Karl Y.;Talamonti, Mark S.;Bentrem, David J.
通讯作者：
Bentrem, David J.