Clinical characteristics of asymptomatic and symptomatic COVID-19 patients in the Eastern Province of Saudi Arabia.

Clinical characteristics of asymptomatic and symptomatic COVID-19 patients in the Eastern Province of Saudi Arabia.
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东部沙特阿拉伯省无症状和有症状的Covid-19患者的临床特征。

DOI:
10.1016/j.jiph.2020.11.002
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发表时间:
2021-01
影响因子:
6.7
通讯作者:
Al-Tawfiq JA
Al-Tawfiq JA
中科院分区:
医学3区
文献类型:
--
作者:
AlJishi JM;Alhajjaj AH;Alkhabbaz FL;AlAbduljabar TH;Alsaif A;Alsaif H;Alomran KS;Aljanobi GA;Alghawi Z;Alsaif M;Al-Tawfiq JA

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沙特阿拉伯第一例COVID-19感染病例于2020年3月2日在卡提夫报告。在这里,我们描述了该地区最初的COVID-19患者的临床特征。这是一项观察性研究,描述了COVID-19病例的临床表现、放射学和实验室数据。2020年3月1日至2020年4月5日,我们共发现82例成人COVID-19患者。患者年龄中位数50岁,年龄范围30 ~ 60岁,以女性54岁(65.9%)居多。其中接触者29例(35.4%),归国人员43例(52.4%),主要为伊拉克归国人员(65%)。50%的患者存在合并症,33%的患者存在G6PD缺乏,27%的患者存在高血压,26%的患者存在糖尿病。有症状者胸片异常占46%,无症状者胸片异常占15.5% (P值= 0.0035)。4例(4.87%)患者需要重症监护。无症状组和有症状组到RT-PCR阴性的平均时间分别为13.6天和16.9天,差异无统计学意义(P值= 0.42)。在沙特阿拉伯最初的COVID-19中心,大多数患者无症状,并且是返回的旅行者。近一半的患者存在合并症。
The first case of COVID-19 infection in Saudi Arabia was reported in Qatif on March 2nd, 2020. Here, we describe the clinical characteristics of the initial COVID-19 patients in that area. This is an observational study describing the clinical presentation, radiographic and laboratory data of COVID-19 cases. From March 1st, 2020 to April 5th, 2020 we identified a total of 82 adult COVID-19 patients. The median age of the patients was 50 years, with a range of 30 to 60 years and most of patients were female 54 (65.9%). Of all the patients, 29 (35.4%) were contacts and 43 (52.4%) were returning travelers, mainly from Iraq (65% of the total returning travelers). Comorbidities were present in 50% of patients, G6PD deficiency in 33%, hypertension in 27%, and diabetes mellitus in 26%. Chest radiographs were abnormal in 46% of symptomatic and 15.5% of asymptomatic patients (P value = 0.0035). Of all patients, 4 (4.87%) required intensive care admission. There was no significant difference in time to negative RT-PCR with mean days to negativity of 13.6 and 16.9 for asymptomatic and symptomatic group, respectively (P value = 0.42). In the initial Epicenter of the COVID-19 in Saudi Arabia, the majority of the patients were asymptomatic and were returning travelers. Comorbidities were present in nearly half of the patients.
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