Regional and global contributions of air pollution to risk of death from COVID-19.

Regional and global contributions of air pollution to risk of death from COVID-19.
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DOI:
10.1093/cvr/cvaa288
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发表时间:
2020-12-01
影响因子:
10.8
通讯作者:
Lelieveld J
Lelieveld J
中科院分区:
医学1区
文献类型:
--
作者:
Pozzer A;Dominici F;Haines A;Witt C;Münzel T;Lelieveld J

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心血管和肺部疾病的合并症会增加 2019 年出现的冠状病毒病 (COVID-19) 的死亡风险。空气污染也会导致这些情况造成的死亡率过高。对2003年首例严重急性呼吸综合征冠状病毒(SARS-CoV-1)结果的分析,以及自2019年以来对SARS-CoV-2结果的初步调查,提供了证据表明其发病率和严重程度与环境空气污染有关。我们估计了因长期暴露于环境细颗粒空气污染而导致的 COVID-19 死亡率的比例。我们根据卫星数据描述了全球细颗粒物暴露情况,并利用大气化学模型计算了人为部分。空气污染对 COVID-19 死亡率的影响程度来自美国和中国的流行病学数据。我们估计,颗粒物空气污染对全球 COVID-19 死亡率约占 15%(95% 置信区间 7-33%),其中东亚为 27%(13-46%),欧洲为 19%(8-41%),北美为 17%(6-39%)。在全球范围内,大约 50-60% 的人为部分与化石燃料的使用有关,在欧洲、西亚和北美高达 70-80%。我们的研究结果表明,空气污染是增加 COVID-19 死亡风险的重要辅助因素。这为将减少空气污染的雄心勃勃的政策与控制 COVID-19 传播的措施结合起来提供了额外的动力。
The risk of mortality from the coronavirus disease that emerged in 2019 (COVID-19) is increased by comorbidity from cardiovascular and pulmonary diseases. Air pollution also causes excess mortality from these conditions. Analysis of the first severe acute respiratory syndrome coronavirus (SARS-CoV-1) outcomes in 2003, and preliminary investigations of those for SARS-CoV-2 since 2019, provide evidence that the incidence and severity are related to ambient air pollution. We estimated the fraction of COVID-19 mortality that is attributable to the long-term exposure to ambient fine particulate air pollution. We characterized global exposure to fine particulates based on satellite data, and calculated the anthropogenic fraction with an atmospheric chemistry model. The degree to which air pollution influences COVID-19 mortality was derived from epidemiological data in the USA and China. We estimate that particulate air pollution contributed ∼15% (95% confidence interval 7–33%) to COVID-19 mortality worldwide, 27% (13 – 46%) in East Asia, 19% (8–41%) in Europe, and 17% (6–39%) in North America. Globally, ∼50–60% of the attributable, anthropogenic fraction is related to fossil fuel use, up to 70–80% in Europe, West Asia, and North America. Our results suggest that air pollution is an important cofactor increasing the risk of mortality from COVID-19. This provides extra motivation for combining ambitious policies to reduce air pollution with measures to control the transmission of COVID-19.
DOI: 10.1016/s0140-6736(17)30505-6
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影响因子: --
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