Reactive oxygen species induced by personal exposure to fine particulate matter emitted from solid fuel combustion in rural Guanzhong Basin, northwestern China
Reactive oxygen species induced by personal exposure to fine particulate matter emitted from solid fuel combustion in rural Guanzhong Basin, northwestern China
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中国西北部关中盆地农村地区因个人接触固体燃料燃烧细颗粒物而产生的活性氧
DOI：
10.1007/s11869-019-00747-z
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发表时间：
2019-09
期刊：
影响因子：
--
通讯作者：
Junji Cao
中科院分区：
文献类型：
--
作者：
Yaqi Li;Hongmei Xu;Kailai He;Jinhui Wang;Zhi Ning;Qiyuan Wang;Nan Li;Zhenxing Shen;Pingping Liu;Jian Sun;Xinyi Niu;Yongxiao Cao;Junji Cao
生活固体燃料燃烧产生的细颗粒物（PM2.5）是我国农村室内环境的重要空气污染物。在这里，个人暴露于PM2.5引起的氧化损伤，导致家庭固体燃料燃烧，在冬季在关中盆地，中国西北部的农村地区进行了检查。50 μ L和100 μL PM2.5提取物的平均外源活性氧（exo-ROS）活性分别为1943.7 ± 3668.0和1628.5 ± 2618.7 μM H2 O2/min/m3。50和100 μL PM2.5提取物处理4 h，内源性活性氧（endo-ROS）的浓度分别为465.8 ± 2427.4和1740.4 ± 2643.2 μM H2 O2/min/m3。当暴露时间延长至24 h时，50和100 μL PM2.5提取物的内-ROS活性分别为3789.5 ± 4582.0和3534.8 ± 4595.6 μM H2 O2/min/m3。在我国西北地区四种常见的采暖方式中，室内煤块炉的ROS活性最高，在50 μL的PM2.5提取物中，4 h内ROS活性为160.4 μM H2 O2/min/m3。结果表明，采用电采暖的农户ROS活性比采用室内煤块炉的农户低2.9-15.9倍，电采暖是农村家庭最清洁的采暖方式。PM2.5中的K+、有机碳1（OC 1）、元素碳1（EC 1）、多环芳烃（PAHs）和2种藿烷类化合物与exo-ROS和4-h endo-ROS显著相关，表明PM2.5暴露样品中的这些化合物及其来源可能诱导更多的ROS，对人体健康产生强烈影响。结果表明，冬季农村家庭使用的取暖方式会通过个人接触PM2.5引起的氧化损伤对中国西北地区农村地区居民的健康产生很大影响。
Fine particulate matter (PM2.5) released by the burning of domestic solid fuels is an important air pollutant in the rural indoor environment in China. Here, personal exposure to PM2.5-induced oxidative damage resulting from household solid fuel combustion was examined in winter in rural areas of Guanzhong Basin, northwestern China. The volume-based average exogenous reactive oxygen species (exo-ROS) activities were 1943.7 ± 3668.0 and 1628.5 ± 2618.7 μM H2O2/min/m3for 50 and 100 μL of PM2.5extracts, respectively. While the different patterns were found for endogenous reactive oxygen species (endo-ROS), 465.8 ± 2427.4 and 1740.4 ± 2643.2 μM H2O2/min/m3for 4 h exposed to 50 and 100 μL of PM2.5extract. When the exposure time was extended to 24 h, endo-ROS activities were 3789.5 ± 4582.0 and 3534.8 ± 4595.6 μM H2O2/min/m3for 50 and 100 μL of PM2.5extracts, respectively. Among four common dwelling heating ways used in northwestern China, the highest ROS activity (160.4 μM H2O2/min/m3for 4-h endo-ROS at 50 μL of PM2.5extracts) was found for households using indoor coal chunks stove. The ROS activity in households using electric power heating was 2.9–15.9-fold lower than that in households using indoor coal chunks stove; thus, electric power heating was found to be the cleanest method for rural household heating. PM2.5-bound K+, organic carbon 1 (OC1), elemental carbon 1 (EC1), several polycyclic aromatic hydrocarbons (PAHs), and two hopanes species were observed to be significantly correlated with exo-ROS and 4-h endo-ROS, indicating that these chemical compounds and the sources in PM2.5exposure samples may induce more ROS and affect human health strongly. The results indicate that heating methods used in rural households in winter can greatly impact the health of residents living in rural areas of northwestern China through personal exposure PM2.5-induced oxidative damage.
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影响因子：
2
作者：
R. Dmochowski
通讯作者：
R. Dmochowski
DOI：
10.1016/j.respe.2020.09.004
发表时间：
2020-10-10
期刊：
Revue D'Epidemiologie et De Sante Publique
影响因子：
--
作者：
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通讯作者：
La rédaction
影响因子：
9.3
作者：
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影响因子：
5.9
作者：
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通讯作者：
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