A Comparison of the Primary Sensory Neurons Used in Olfaction and Vision.

A Comparison of the Primary Sensory Neurons Used in Olfaction and Vision.
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DOI:
10.3389/fncel.2020.595523
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发表时间:
2020
影响因子:
5.3
通讯作者:
Baker SA
Baker SA
中科院分区:
医学2区
文献类型:
--
作者:
Lankford CK;Laird JG;Inamdar SM;Baker SA

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视觉、听觉、嗅觉、味觉和触觉是用来感知和驾驭世界的工具。它们使我们能够获得必要的资源,如食物和高度渴望的资源,如配偶。由于对生物医学研究的投资,我们对人类感觉的分子分析只能与我们对实验室老鼠的感觉的了解相媲美。人类严重依赖视觉,而老鼠则以嗅觉为主要感官。这两种模式都有许多共同的特点,首先是由高度特化的初级感觉神经元进行信号检测——杆状和锥状感光细胞(PR)负责视觉,嗅觉感觉神经元(OSN)负责嗅觉。在本章中,我们概述了这两种类型的初级感觉神经元是如何运作的,同时强调了它们的相似之处和区别。
Vision, hearing, smell, taste, and touch are the tools used to perceive and navigate the world. They enable us to obtain essential resources such as food and highly desired resources such as mates. Thanks to the investments in biomedical research the molecular unpinning’s of human sensation are rivaled only by our knowledge of sensation in the laboratory mouse. Humans rely heavily on vision whereas mice use smell as their dominant sense. Both modalities have many features in common, starting with signal detection by highly specialized primary sensory neurons—rod and cone photoreceptors (PR) for vision, and olfactory sensory neurons (OSN) for the smell. In this chapter, we provide an overview of how these two types of primary sensory neurons operate while highlighting the similarities and distinctions.
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