Concentric electrodes improve microfluidic droplet sorting.

Concentric electrodes improve microfluidic droplet sorting.
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DOI:
10.1039/c7lc01242j
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发表时间:
2018-02-27
期刊:
影响因子:
6.1
通讯作者:
Abate AR
Abate AR
中科院分区:
工程技术1区
文献类型:
--
作者:
Clark IC;Thakur R;Abate AR

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Microfluidic droplet sorting allows selection of subpopulations of cells, nucleic acids, and biomolecules with soluble assays. Dielectrophoresis is widely used for sorting because it generates strong forces on droplets, actuates rapidly, and is easy to integrate into microfluidic chips. However, existing device designs apply a short force, limiting the deflection of droplets and, therefore, the speed and reliability of sorting. We describe a concentric design that applies a long force, allowing large deflections and increased reliability. We demonstrate the utility of this design by sorting polydispersed emulsions, which are typically difficult to sort with high purity. Concentric electrodes generate a uniform dielectrophoretic force that enhances droplet sorting reliability.
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