Feasibility and Preliminary Efficacy of Tailored Yoga in Survivors of Head and Neck Cancer: A Pilot Study.
Feasibility and Preliminary Efficacy of Tailored Yoga in Survivors of Head and Neck Cancer: A Pilot Study.
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DOI：
10.1177/1534735417753540
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发表时间：
2018-09
影响因子：
2.9
通讯作者：
Ridner SH
中科院分区：
文献类型：
--
作者：
Adair M;Murphy B;Yarlagadda S;Deng J;Dietrich MS;Ridner SH
目的：头颈癌（HNC）的治疗会导致长期毒性，并增加幸存者的身体和心理负担。对于这些晚期效应的治疗方法有限。瑜伽姿势，呼吸工作，放松和冥想，可以改善这些后期效果。本研究的目的是研究HNC幸存者量身定制的瑜伽课程的可行性，并获得初步的疗效数据。方法：这是一项针对癌症治疗后>3个月的瑜伽初治HNC幸存者的随机等待列表对照研究。收集基线数据。参与者被随机分配到为期8周的哈他瑜伽干预组或等待组。收集可行性和有效性数据。在第4周和第8周，患者接受了重复的健康评估。等待名单控制组参与者在数据收集后提供瑜伽课程。描述性统计评价可行性。使用混合效应一般线性模型生成疗效结局的估计值。结果：73人被筛选，40人合格。所有符合条件的个人均同意并入组。干预组中有5人提前停药，等待名单对照组中没有人停药。可行性得到了肯定，因为参与者被招募并保留在研究中，没有不良事件，证明了对方案的忠诚，满意率很高。疗效指标显示，肩关节活动度（d = 0.57-0.86，P <0.05）、疼痛（d = 0.67-0.90，P ≤ 0.005）和焦虑（d = 0.59，P = 0.015）可能受益。结论：量身定制的哈他瑜伽计划是可行的，并可能有效的HNC幸存者。初步数据支持进一步调查瑜伽在这一人群中是必要的。
Purpose: Treatment for head and neck cancer (HNC) results in long-term toxicities and increased physical and psychosocial survivor burden. There are a limited number of treatments for these late effects. Yoga postures, breath work, relaxation, and meditation, may improve these late effects. The purpose of this study was to examine the feasibility of a tailored yoga program in HNC survivors and obtain preliminary efficacy data. Methods: This was a randomized wait-list control study of yoga-naive HNC survivors who were >3 months post–cancer treatment. Baseline data were collected. Participants were randomized to either an 8-week hatha yoga intervention group or a wait-list group. Feasibility and efficacy data were collected. At 4 and 8 weeks, patients underwent a repeat assessment of health. Wait-list control group participants were offered the yoga program after data collection. Descriptive statistics evaluated feasibility. Mixed effects general linear models were used to generate estimates of the efficacy outcomes. Results: Seventy-three individuals were screened and 40 were eligible. All eligible individuals consented and enrolled. Five of the intervention group discontinued early and none in the wait-list control group. Feasibility was affirmed as participants were recruited and retained in the study, there were no adverse events, fidelity to protocol was demonstrated, and satisfaction rates were high. Efficacy measures indicated potential benefit for shoulder range of motion (d = 0.57-0.86, P < .05), pain (d = 0.67-0.90, P ≤ .005), and anxiety (d = 0.59, P = .015). Conclusion: A tailored hatha yoga program is feasible and potentially efficacious for HNC survivors. Preliminary data supports further investigation of yoga in this population is needed.
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影响因子：
4.7
作者：
Atkinson, Thomas M.;Rosenfeld, Barry D.;Sit, Laura;Mendoza, Tito R.;Fruscione, Mike;Lavene, Dawn;Shaw, Mary;Li, Yuelin;Hay, Jennifer;Cleeland, Charles S.;Scher, Howard I.;Breitbart, William S.;Basch, Ethan
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作者：
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DOI：
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发表时间：
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影响因子：
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作者：
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通讯作者：
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DOI：
10.1111/j.1749-6632.2009.04394.x
发表时间：
2009-01-01
期刊：
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影响因子：
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作者：
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影响因子：
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作者：
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通讯作者：
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