Many paths to alopecia via compromised regeneration of hair follicle stem cells.

Many paths to alopecia via compromised regeneration of hair follicle stem cells.
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DOI:
10.1038/jid.2012.511
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发表时间:
2013-06
影响因子:
6.5
通讯作者:
Chuong, Cheng Ming
Chuong, Cheng Ming
中科院分区:
医学1区
文献类型:
--
作者:
Li, Ji;Jiang, Ting Xin;Chuong, Cheng Ming

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脱发可能是由于毛囊的缺陷形成或破坏增加。许多工作已经阐明了控制脱发所造成的再生问题,由于形态信号。最近,研究人员开始揭示毛干细胞活化和发展所需的核途径。这些研究将为治疗策略的设计提供新的线索。
Alopecia can be caused by defective formation or increased destruction of hair follicles. Much work has elucidated the control of alopecia caused by regenerative problems due to morphogen signaling. Recently investigators started to reveal nuclear pathways required for the activation and progression of hair stem cells. Taken together these studies will provide new clues to the design of therapeutic strategies.
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