Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.
复制标题

DOI:
10.1016/j.chom.2009.06.006
复制
发表时间:
2009-07-23
影响因子:
30.3
通讯作者:
Ziegler P
Ziegler P
中科院分区:
医学1区
文献类型:
--
作者:
Legrand N;Ploss A;Balling R;Becker PD;Borsotti C;Brezillon N;Debarry J;de Jong Y;Deng H;Di Santo JP;Eisenbarth S;Eynon E;Flavell RA;Guzman CA;Huntington ND;Kremsdorf D;Manns MP;Manz MG;Mention JJ;Ott M;Rathinam C;Rice CM;Rongvaux A;Stevens S;Spits H;Strick-Marchand H;Takizawa H;van Lent AU;Wang C;Weijer K;Willinger T;Ziegler P

文献摘要

参考文献

被引文献

相似文献

全球有超过 8 亿人感染肝炎病毒、人类免疫缺陷病毒 (HIV) 和疟疾,每年导致超过 500 万人死亡。在这里,我们讨论人源化小鼠模型在开发有效且负担得起的疗法和疫苗方面的潜力和挑战,这些疗法和疫苗是对抗这些疾病所迫切需要的。
Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.
DOI: 10.1038/nbt1326
发表时间: 2007-08-01
影响因子: 46.9
作者:
Azuma, Hisaya;Paulk, Nicole;Grompe, Markus
通讯作者: Grompe, Markus
DOI: 10.1038/90968
发表时间: 2001-08-01
期刊: NATURE MEDICINE
影响因子: 82.9
作者:
Mercer, DF;Schiller, DE;Kneteman, NM
通讯作者: Kneteman, NM
DOI: 10.1371/journal.pmed.0050016
发表时间: 2008-01-15
期刊: PLoS medicine
影响因子: 15.8
作者:
Denton PW;Estes JD;Sun Z;Othieno FA;Wei BL;Wege AK;Powell DA;Payne D;Haase AT;Garcia JV
通讯作者: Garcia JV
DOI: 10.1126/science.1093933
发表时间: 2004-04-02
期刊: SCIENCE
影响因子: 56.9
作者:
Traggiai, E;Chicha, L;Manz, MG
通讯作者: Manz, MG
DOI: 10.1126/science.1160355
发表时间: 2008-07-25
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Grant RM;Hamer D;Hope T;Johnston R;Lange J;Lederman MM;Lieberman J;Miller CJ;Moore JP;Mosier DE;Richman DD;Schooley RT;Springer MS;Veazey RS;Wainberg MA
通讯作者: Wainberg MA