Ethnicity and psychiatric comorbidity in a national sample: evidence for latent comorbidity factor invariance and connections with disorder prevalence.

Ethnicity and psychiatric comorbidity in a national sample: evidence for latent comorbidity factor invariance and connections with disorder prevalence.
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DOI:
10.1007/s00127-012-0595-5
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发表时间:
2013-05
影响因子:
4.4
通讯作者:
Hasin, Deborah S.
Hasin, Deborah S.
中科院分区:
医学2区
文献类型:
--
作者:
Eaton, Nicholas R.;Keyes, Katherine M.;Krueger, Robert F.;Noordhof, Arjen;Skodol, Andrew E.;Markon, Kristian E.;Grant, Bridget F.;Hasin, Deborah S.

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许多常见精神障碍的患病率和双变量共病模式在不同种族之间存在显著差异。虽然研究已经检查了性别和年龄的多变量共病模式,但据我们所知,没有研究检查了种族的这种模式。这样的调查可以帮助理解精神健康中与种族相关的健康差异的性质,并且考虑到可能实施多变量共病结构(即,内化和外化),以构建DSM-5的关键部分。我们调查了11种常见精神障碍的多变量共病性及其相关的潜在共病性因素是否在一个大型的全国代表性样本(N = 43,093)中的五个种族群体中存在差异。我们在白色(n = 24,507)、西班牙裔/拉丁裔(n = 8,308)、黑人(n = 8,245)、亚洲/太平洋岛民(n = 1,332)和美洲印第安人/阿拉斯加原住民(n = 701)个体中进行了验证性因子分析和因子不变性分析。结果支持两个因素的内化-外化共病因素模型在终身和12个月的诊断。这种结构在不同种族之间是不变的,但不同种族之间的因素均值差异显着。这些研究结果,放在一起,表明,观察到的患病率种族群体之间的差异反映了种族差异的潜在内化和外化因素的手段。我们讨论了分类(DSM-5和ICD-11元结构),健康差异研究和治疗的影响。
Prevalence rates, and bivariate comorbidity patterns, of many common mental disorders differ significantly across ethnic groups. While studies have examined multivariate comorbidity patterns by gender and age, no studies to our knowledge have examined such patterns by ethnicity. Such an investigation could aid in understanding the nature of ethnicity-related health disparities in mental health and is timely given the likely implementation of multivariate comorbidity structures (i.e., internalizing and externalizing) to frame key parts of DSM-5. We investigated whether multivariate comorbidity of 11 common mental disorders, and their associated latent comorbidity factors, differed across five ethnic groups in a large, nationally representative sample (N = 43,093). We conducted confirmatory factor analyses and factorial invariance analyses in White (n = 24,507), Hispanic/Latino (n = 8,308), Black (n = 8,245), Asian/Pacific Islander (n = 1,332), and American Indian/Alaska Native (n = 701) individuals. Results supported a two-factor internalizing-externalizing comorbidity factor model in both lifetime and 12-month diagnoses. This structure was invariant across ethnicity, but factor means differed significantly across ethnic groups. These findings, taken together, indicated that observed prevalence rate differences between ethnic groups reflect ethnic differences in latent internalizing and externalizing factor means. We discuss implications for classification (DSM-5 and ICD-11 meta-structure), health disparities research, and treatment.
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