FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster.

FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster.
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Flyatlas:果蝇组织组织中基因表达的数据库。

DOI:
10.1093/nar/gks1141
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发表时间:
2013-01
影响因子:
14.9
通讯作者:
Leader DP
Leader DP
中科院分区:
生物学2区
文献类型:
--
作者:
Robinson SW;Herzyk P;Dow JA;Leader DP

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FlyAtlas资源包含通过将信使RNA与Affymetrix Drosophila Genome 2微阵列杂交获得的不同组织(目前为25-17只成虫和8只幼虫)中黑腹果蝇基因表达的数据。该微阵列探针集覆盖13 250个果蝇基因,以明确的方式检测12 533个。原始web应用程序(http://flyatlas.org)的底层数据已经重构为关系数据库和Java servlet,以提供新的web界面FlyAtlas 2 (http://flyatlas.gla.ac)。Uk /),它允许几个额外的查询。用户可以检索属于相同或相关本体论类别的单个基因或基因组的数据。Ajax“自动建议”功能提供了选择有效搜索词的帮助,该功能在用户键入时轮询数据库。搜索也可以集中在特定的组织上,并且可以检索到表达最高的基因,表达高于平均水平的特定类别的基因或在幼虫和成虫阶段表达差异最大的基因的数据。一种新的设备允许对数据库进行特定基因的查询,以找到在不同组织中具有相似表达模式的其他基因。
The FlyAtlas resource contains data on the expression of the genes of Drosophila melanogaster in different tissues (currently 25—17 adult and 8 larval) obtained by hybridization of messenger RNA to Affymetrix Drosophila Genome 2 microarrays. The microarray probe sets cover 13 250 Drosophila genes, detecting 12 533 in an unambiguous manner. The data underlying the original web application (http://flyatlas.org) have been restructured into a relational database and a Java servlet written to provide a new web interface, FlyAtlas 2 (http://flyatlas.gla.ac.uk/), which allows several additional queries. Users can retrieve data for individual genes or for groups of genes belonging to the same or related ontological categories. Assistance in selecting valid search terms is provided by an Ajax ‘autosuggest’ facility that polls the database as the user types. Searches can also focus on particular tissues, and data can be retrieved for the most highly expressed genes, for genes of a particular category with above-average expression or for genes with the greatest difference in expression between the larval and adult stages. A novel facility allows the database to be queried with a specific gene to find other genes with a similar pattern of expression across the different tissues.
DOI: 10.1101/gr.169101
发表时间: 2001-06-01
期刊: GENOME RESEARCH
影响因子: 7
作者:
Reiter, LT;Potocki, L;Bier, E
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Flybase 101-导航Flybase的基础。
DOI: 10.1093/nar/gkr1030
发表时间: 2012-01
影响因子: 14.9
作者:
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DOI: 10.1186/gb-2007-8-7-r129
发表时间: 2007
期刊: Genome biology
影响因子: 12.3
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发表时间: 2007-06-01
期刊: NATURE GENETICS
影响因子: 30.8
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