Experimental evolution of specialization by a microsporidian parasite.
Experimental evolution of specialization by a microsporidian parasite.
复制标题
DOI：
10.1186/1471-2148-10-159
复制
发表时间：
2010-05-28
影响因子：
3.4
通讯作者：
Koella JC
中科院分区：
文献类型：
--
作者：
Legros M;Koella JC
进化理论预测，寄生虫专化一种宿主或成为广泛宿主的通才的压力是由宿主种群的多样性或时间变异性以及适应不同宿主的遗传权衡所驱动的。我们给这个想法的实验证据，让寄生虫Brachiola algerae进化的四个遗传同质线的蚊子埃及伊蚊的一个，在四个线的混合物或交替序列的四个线。第一种制度预期会培养出专家，另外两种制度则会培养出通才。经过13代，我们在蚊子的四条线上测试了进化的寄生虫。专门的寄生虫是最具感染性的对自己的isofemale线和其他isofemale线感染性最低，而通才寄生虫有中间感染成功的所有线路。专家在其匹配的蚊子线上的成功与其在其他线上的成功呈负相关，这表明专业化的进化成本。观察到通才在所有同雌品系上的平均感染性高于专家，证实了这种权衡。总的来说，我们的实验揭示了寄生虫的专业化，其主机的个人基因型的潜力，并提供了实验证据的成本与专业化的演变，一个重要的功能，了解主机和寄生虫之间的共同进化动力学。
Evolutionary theory predicts that the pressure for parasites to specialize on one host or to become generalists on a wide range of hosts is driven by the diversity or temporal variability of the host's population and by genetic trade-offs in the adaptation to different hosts. We give experimental evidence for this idea by letting the parasite Brachiola algerae evolve on one of four genetically homogeneous lines of the mosquito Aedes aegypti, on a mixture of the four lines or on an alternating sequence of the four lines. The first regime was expected to lead to specialists, the other two to generalists. After 13 generations, we tested the evolved parasites on each of the four lines of the mosquito. The specialized parasites were most infective on their own isofemale line and least infective on other isofemale lines, while the generalist parasites had intermediate infection success on all lines. The success of a specialist on its matched mosquito line was negatively correlated with its success on other lines, suggesting an evolutionary cost to specialization. This trade-off was corroborated by the observation that the generalists had higher average mean infectivity than the specialists over all isofemale lines. Overall, our experiment reveals the potential for specialization of a parasite to individual genotypes of its host and provides experimental evidence of the cost associated with the evolution of specialization, an important feature for understanding the coevolutionary dynamics between hosts and parasites.
登录
查看更多内容
影响因子：
64.8
作者：
Cooper, VS;Lenski, RE
通讯作者：
Lenski, RE
影响因子：
3.3
作者：
Little, TJ;Watt, K;Ebert, D
通讯作者：
Ebert, D
影响因子：
3.4
作者：
Hansen, MHH;Koella, JC
通讯作者：
Koella, JC
影响因子：
3.3
作者：
VIA, S;LANDE, R
通讯作者：
LANDE, R
影响因子：
1.6
作者：
Becnel, JJ;White, SE;Shapiro, AM
通讯作者：
Shapiro, AM