The expanding implications of polyploidy.
The expanding implications of polyploidy.
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DOI:
10.1083/jcb.201502016
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发表时间:
2015-05-25
期刊:
影响因子:
--
通讯作者:
Fox DT
中科院分区:
文献类型:
--
作者:
Schoenfelder KP;Fox DT
Polyploid cells, which contain more than two genome copies, occur throughout nature. Beyond well-established roles in increasing cell size/metabolic output, polyploidy can also promote nonuniform genome, transcriptome, and metabolome alterations. Polyploidy also frequently confers resistance to environmental stresses not tolerated by diploid cells. Recent progress has begun to unravel how this fascinating phenomenon contributes to normal physiology and disease.
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