Population differentiation and migration: coalescence times in a two-sex island model for autosomal and X-linked loci.
Population differentiation and migration: coalescence times in a two-sex island model for autosomal and X-linked loci.
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DOI:
10.1016/j.tpb.2008.08.003
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发表时间:
2008-12
影响因子:
1.4
通讯作者:
Wakeley, John
中科院分区:
文献类型:
--
作者:
Ramachandran, Sohini;Rosenberg, Noah A.;Feldman, Marcus W.;Wakeley, John
Evolutionists have debated whether population-genetic parameters, such as effective population size and migration rate, differ between males and females. In humans, most analysis of this problem has focused on the Y chromosome and the mitochondrial genome, while the X chromosome has largely been omitted from the discussion. Past studies have compared FST values for the Y and mitochondrion under a model with migration rates that differ between the sexes but with equal male and female population sizes. In this study we investigate rates of coalescence for X-linked and autosomal lineages in an island model with different population sizes and migration rates for males and females, obtaining the mean time to coalescence for pairs of lineages from the same deme and for pairs of lineages from different demes. We apply our results to microsatellite data from the Human Genome Diversity Panel, and we examine the male and female migration rates implied by observed FST values.
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影响因子:
56.9
作者:
Rosenberg, NA;Pritchard, JK;Feldman, MW
通讯作者:
Feldman, MW
影响因子:
30.8
作者:
Oota, H;Settheetham-Ishida, W;Stoneking, M
通讯作者:
Stoneking, M
影响因子:
1.9
作者:
Rosenberg, Noah A.
通讯作者:
Rosenberg, Noah A.
影响因子:
30.8
作者:
Seielstad, MT;Minch, E;Cavalli-Sforza, LL
通讯作者:
Cavalli-Sforza, LL
DOI:
10.1073/pnas.0507611102
发表时间:
2005-11-01
影响因子:
11.1
作者:
Ramachandran, S;Deshpande, O;Cavalli-Sforza, LL
通讯作者:
Cavalli-Sforza, LL