Population differentiation and migration: coalescence times in a two-sex island model for autosomal and X-linked loci.

Population differentiation and migration: coalescence times in a two-sex island model for autosomal and X-linked loci.
复制标题

DOI:
10.1016/j.tpb.2008.08.003
复制
发表时间:
2008-12
影响因子:
1.4
通讯作者:
Wakeley, John
Wakeley, John
中科院分区:
生物学4区
文献类型:
--
作者:
Ramachandran, Sohini;Rosenberg, Noah A.;Feldman, Marcus W.;Wakeley, John

文献摘要

参考文献

被引文献

相似文献

进化论者一直在争论种群遗传参数,如有效种群规模和迁移率,是否在男性和女性之间存在差异。在人类中,对这个问题的大多数分析都集中在Y染色体和线粒体基因组上,而X染色体在很大程度上被忽略了。过去的研究在一个模型下比较了Y和Ekon的FST值,该模型的迁移率在性别之间不同,但男性和女性人口规模相同。在这项研究中,我们调查的合并率为X连锁和常染色体谱系在岛屿模型与不同的人口规模和迁移率的男性和女性,获得平均时间合并的对血统从同一个德梅和对血统从不同德梅。我们将我们的研究结果应用于人类基因组多样性小组的微卫星数据,我们研究了所观察到的FST值所暗示的男性和女性迁移率。
Evolutionists have debated whether population-genetic parameters, such as effective population size and migration rate, differ between males and females. In humans, most analysis of this problem has focused on the Y chromosome and the mitochondrial genome, while the X chromosome has largely been omitted from the discussion. Past studies have compared FST values for the Y and mitochondrion under a model with migration rates that differ between the sexes but with equal male and female population sizes. In this study we investigate rates of coalescence for X-linked and autosomal lineages in an island model with different population sizes and migration rates for males and females, obtaining the mean time to coalescence for pairs of lineages from the same deme and for pairs of lineages from different demes. We apply our results to microsatellite data from the Human Genome Diversity Panel, and we examine the male and female migration rates implied by observed FST values.
DOI: 10.1126/science.1078311
发表时间: 2002-12-20
期刊: SCIENCE
影响因子: 56.9
作者:
Rosenberg, NA;Pritchard, JK;Feldman, MW
通讯作者: Feldman, MW
DOI: 10.1038/ng711
发表时间: 2001-09-01
期刊: NATURE GENETICS
影响因子: 30.8
作者:
Oota, H;Settheetham-Ishida, W;Stoneking, M
通讯作者: Stoneking, M
DOI: 10.1111/j.1469-1809.2006.00285.x
发表时间: 2006-11-01
影响因子: 1.9
作者:
Rosenberg, Noah A.
通讯作者: Rosenberg, Noah A.
DOI: 10.1038/3088
发表时间: 1998-11-01
期刊: NATURE GENETICS
影响因子: 30.8
作者:
Seielstad, MT;Minch, E;Cavalli-Sforza, LL
通讯作者: Cavalli-Sforza, LL
DOI: 10.1073/pnas.0507611102
发表时间: 2005-11-01
影响因子: 11.1
作者:
Ramachandran, S;Deshpande, O;Cavalli-Sforza, LL
通讯作者: Cavalli-Sforza, LL