Hippocampal neurons code individual episodic memories in humans
Hippocampal neurons code individual episodic memories in humans
复制标题
海马神经元编码人类的个体情景记忆
DOI:
10.1101/2021.06.28.450149
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发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Kolibius L
中科院分区:
文献类型:
--
作者:
Kolibius L
The hippocampus is an essential hub for episodic memory processing. However, how human hippocampal single neurons code multi-element associations remains unknown. In particular, it is debated whether each hippocampal neuron represents an invariant element within an episode or whether single neurons bind together all the elements of a discrete episodic memory. Here we provide evidence for the latter hypothesis. Using single-neuron recordings from a total of 30 participants, we show that individual neurons, which we term episode-specific neurons, code discrete episodic memories using either a rate code or a temporal firing code. These neurons were observed exclusively in the hippocampus. Importantly, these episode-specific neurons do not reflect the coding of a particular element in the episode (that is, concept or time). Instead, they code for the conjunction of the different elements that make up the episode.
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DOI:
--
发表时间:
2021
期刊:
International Conference on Learning Representations
影响因子:
--
作者:
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通讯作者:
T. Behrens
影响因子:
5.3
作者:
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通讯作者:
Duezel, Emrah
影响因子:
3.7
作者:
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通讯作者:
Mormann F
影响因子:
5.1
作者:
Prestigio, Cosimo;Ferrante, Daniele;Baldelli, Pietro
通讯作者:
Baldelli, Pietro
DOI:
--
发表时间:
2020-08
期刊:
ArXiv
影响因子:
--
作者:
D. Krotov;J. Hopfield
通讯作者:
D. Krotov;J. Hopfield