Evaluation of Urinary Sphincter Function by Rapid Magnetic Resonance Diffusion Tensor Imaging.
Evaluation of Urinary Sphincter Function by Rapid Magnetic Resonance Diffusion Tensor Imaging.
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DOI：
10.5213/inj.2040208.104
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发表时间：
2020-12
影响因子：
2.3
通讯作者：
Eberli D
中科院分区：
文献类型：
--
作者：
Schmid FA;Gomolka RS;Hötker AM;Boss A;Kessler TM;Rossi C;Eberli D
本研究旨在评估快速扩散张量成像（DTI）的可行性，评价女性尿道括约肌功能的基础上区分休息和肌肉收缩。2019年6月至7月，在3特斯拉下对10名健康女性志愿者（21-36岁;体重指数，20.8±3.6 kg/m2）进行了下骨盆磁共振成像（MRI）。获取高分辨率T1和T2加权图像作为解剖参考，并在4个实验阶段进行DTI：休息（表示休息-1，2）和收缩（表示收缩-1，2）两次。由2名独立的阅片师对尿道括约肌和提肛肌进行手动分割。平均扩散率（MD）和各向异性分数（FA）值来自DTI体积进行了比较，以寻找实验阶段之间的显着差异。通过组内相关系数（ICC）评估阅片者之间的一致性。Kruskal-Wallis检验显示所有实验阶段之间的MD值之间存在显著差异，由两个独立的读取器（第一：X2 [3，76]=17.16，P<0.001和第二：X2 [3，76]=15.88，P<0.01）。事后分析显示，两名阅片者的MD值存在差异：静息-1 vs.收缩-1（至少P<0.05）、静息-1 vs.收缩-2（P<0.01）、静息-2 vs.收缩-1（P<0.03）、静息-2 vs.收缩-2（P=0.02），总体平均“静息”与“收缩”ΔMD= 20.6%。在所有实验阶段中，未发现休息-1与休息-2和收缩-1与收缩-2之间的MD或FA差异，阅读者间一致性为ICC=0.85（MD）和ICC=0.79（FA）。快速扩散张量成像可作为女性骨盆底肌肉功能及尿失禁评估的辅助工具。
This study aimed to assess the feasibility of a rapid diffusion tensor imaging (DTI) for evaluation of the female urinary sphincter function based on differentiation between rest and muscle contraction. Magnetic resonance imaging (MRI) of the lower pelvis was performed at 3 Tesla in 10 healthy female volunteers (21–36 years; body mass index, 20.8±3.6 kg/m2) between June and July 2019. High-resolution T1- and T2-weighted images were acquired for anatomical reference, and following DTI performed in 4 experiment phases: twice during rest (denoted rest-1, rest-2) and contraction (contraction-1, contraction-2). Manual segmentation of the urinary sphincter and the levator ani muscles were performed by 2 independent readers. Mean diffusivity (MD) and fractional anisotropy (FA) values derived from DTI volumes were compared in search for significant differences between the experiment phases. Interreader agreement was assessed by intraclass correlation coefficient (ICC). Kruskal-Wallis test showed significant differences between MD values among all the experiment phases, by both independent readers (1st: X2 [3,76]=17.16, P<0.001 and 2nd: X2 [3,76]=15.88, P<0.01). Post hoc analysis revealed differences in MD values by both readers between: rest-1 vs. contraction-1 (least P<0.05), rest-1 vs. contraction-2 (P<0.01), rest-2 vs. contraction-1 (P<0.03), rest-2 vs. contraction-2 (P=0.02) with overall mean ‘rest’ to ‘contraction’ ΔMD=20.6%. No MD or FA differences were found between rest-1 vs. rest-2 and contraction-1 vs. contraction-2 among all the experiment phases, and interreader agreement was ICC=0.85 (MD) and ICC=0.79 (FA). Rapid DTI might prospectively act as a supporting tool for the evaluation of female pelvic floor muscle function, and incontinence assessment.
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影响因子：
3.3
作者：
Damon, Bruce M.
通讯作者：
Damon, Bruce M.
影响因子：
4.4
作者：
Hatakenaka, Masamitsu;Matsuo, Yoshio;Honda, Hiroshi
通讯作者：
Honda, Hiroshi
DOI：
10.1016/j.jmr.2011.09.022
发表时间：
1996-06-01
期刊：
JOURNAL OF MAGNETIC RESONANCE SERIES B
影响因子：
--
作者：
Basser, PJ;Pierpaoli, C
通讯作者：
Pierpaoli, C
影响因子：
4.4
作者：
Polders, Daniel L.;Leemans, Alexander;Hoogduin, Johannes M.
通讯作者：
Hoogduin, Johannes M.
DOI：
10.1016/j.jmr.2011.08.023
发表时间：
2011-12-01
期刊：
Journal of magnetic resonance (San Diego, Calif. : 1997)
影响因子：
--
作者：
Basser, Peter;Pierpaoli, Carlo
通讯作者：
Pierpaoli, Carlo